Please use this identifier to cite or link to this item:
Title: Two New Polymorphic Cocrystals of Zafirlukast: Preparation, Crystal Structure, and Stability Relations
Author: Llinàs, Antonio
Barbas Cañero, Rafael
Font Bardia, Ma. Mercedes
Quayle, M. J.
Velaga, S.
Prohens López, Rafael
Keywords: Estructura cristal·lina (Sòlids)
Química supramolecular
Layer structure (Solids)
Supramolecular chemistry
Issue Date: 2015
Publisher: American Chemical Society
Abstract: Two new cocrystals of zafirlukast with piperazine, existing in five different solid forms, have been discovered during a cocrystal screening. The crystal structure of one of these forms has been determined by single crystal X-ray diffraction, and the stability landscape of the crystalline forms of the new cocrystal has been studied. In the present article, we extend the knowledge about the solid state of this important pharmaceutical drug for the treatment of asthma by reporting the crystal structures of two new solvates (acetonitrile and butanol) and the elusive anhydrous Form X, which have been solved by single crystal X-ray diffraction.
Note: Versió postprint del document publicat a:
It is part of: Crystal Growth & Design, 2015, vol. 15, num. 8, p. 4162-4169
Related resource:
ISSN: 1528-7483
Appears in Collections:Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada)

Files in This Item:
File Description SizeFormat 
693069.pdf2.09 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.