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Title: Centrosomes in asymmetric cell division
Author: González, Cayetano
Keywords: Divisió cel·lular
Cell division
Issue Date: 3-Dec-2020
Publisher: Elsevier
Abstract: Asymmetric cell division (ACD) is a strategy for achieving cell diversity. Research carried out over the last two decades has shown that in some cell types that divide asymmetrically, mother and daughter centrosomes are noticeably different from one another in structure, behaviour, and fate, and that robust ACD depends upon centrosome function. Here, I review the latest advances in this field with special emphasis on the complex structure-function relationship of centrosomes with regards to ACD and on mechanistic insight derived from cell types that divide symmetrically but is likely to be relevant in ACD. I also include a comment arguing for the need to investigate the centrosome cycle in other cell types that divide asymmetrically.
Note: Versió postprint del document publicat a:
It is part of: Current Opinion in Structural Biology, 2021, vol. 66, p. 178-182
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ISSN: 6456794
Appears in Collections:Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))

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