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dc.contributor.authorHernáez Camba, Álvaro-
dc.contributor.authorLassale, Camille-
dc.contributor.authorCastro Barquero, Sara-
dc.contributor.authorBabio, Nancy-
dc.contributor.authorRos Rahola, Emilio-
dc.contributor.authorCastañer, Olga-
dc.contributor.authorTresserra i Rimbau, Anna-
dc.contributor.authorPintó Sala, Xavier-
dc.contributor.authorMartínez-González, Miguel Ángel, 1957--
dc.contributor.authorCorella Piquer, Dolores-
dc.contributor.authorSalas Salvadó, Jordi-
dc.contributor.authorAlonso Gómez, Ángel M.-
dc.contributor.authorLapetra, José-
dc.contributor.authorFiol Sala, Miguel-
dc.contributor.authorGómez Gracia, Enrique-
dc.contributor.authorSerra Majem, Lluís-
dc.contributor.authorSacanella Meseguer, Emilio-
dc.contributor.authorGarcia-Arellano, Ana-
dc.contributor.authorSorlí, José V.-
dc.contributor.authorDíaz López, Andrés-
dc.contributor.authorCofán Pujol, Montserrat-
dc.contributor.authorEstruch Riba, Ramon-
dc.description.abstractWe aimed to assess the effects of the antioxidant-rich Mediterranean diet (MedDiet) onwhite blood cell count. Our study population included participants in the PREvención con DIetaMEDiterránea study (average age 67 years old, 58% women, high cardiovascular risk). We assessedwhether a MedDiet intervention enriched in extra-virgin olive oil or nuts, versus a low-fat controldiet, modified the incidence of leukocytosis (>11×109leukocytes/L), mild leukopenia (<4.5×109leukocytes/L), or severe leukopenia (<3.5×109leukocytes/L) in individuals without the conditionat baseline (n= 3190,n= 2925, andn= 3190, respectively). We also examined whether MedDietmodified the association between leukocyte count alterations and all-cause mortality. Both MedDietinterventions were associated with a lower risk of developing leukopenia (incidence rates: 5.06%in control diet, 3.29% in MedDiet groups combined; hazard ratio [95% confidence interval]: 0.54[0.36-0.80]) and severe leukopenia (incidence rates: 1.26% in control diet, 0.46% in MedDiet groupscombined; hazard ratio: 0.25 [0.10-0.60]). High cumulative adherence to a MedDiet was linked tolower risk of leukocytosis (incidence rates: 2.08% in quartile 1, 0.65% in quartile 4; HRQ4-Q1: 0.29[0.085-0.99]) and attenuated the association between leukopenia and all-cause mortality (P-interaction= 0.032). In brief, MedDiet decreased the incidence of white blood cell count-related alterations inhigh cardiovascular risk individuals.-
dc.relation.isformatofReproducció del document publicat a:
dc.relation.ispartofFoods, 2021, vol. 10, num. 6, p. 1268-
dc.rightscc-by (c) Hernáez Camba, Álvaro et al., 2021-
dc.subject.classificationCuina mediterrània-
dc.subject.classificationMalalties hematològiques-
dc.subject.otherMediterranean cooking-
dc.subject.otherHematologic diseases-
dc.titleMediterranean diet and white blood cell count - A randomized controlled trial.-
Appears in Collections:Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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