Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/180328
Title: | Efficient long-range conduction in cable bacteria through nickel protein wires |
Author: | Boschker, Henricus T. S. Cook, Perran L. M. Polerecky, Lubos Eachambadi, Raghavendran Thiruvallur Lozano, Helena Hidalgo Martinez, Silvia Khalenkow, Dmitry Spampinato, Valentina Claes, Nathalie Kundu, Paromita Wang, Da Bals, Sara Sand, Karina K. Cavezza, Francesca Hauffman, Tom Bjerg, Jesper Tataru Skirtach, Andre G. Kochan, Kamila McKee, Merrilyn Wood, Bayden Bedolla, Diana Gianoncelli, Alessandra Geerlings, Nicole M. J. Van Gerven, Nani Remaut, Han Geelhoed, Jeanine S. Millán Solsona, Rubén Fumagalli, Laura Nielsen, Lars Peter Franquet, Alexis Manca, Jean V. Gomila Lluch, Gabriel Meysman, Filip J. R. |
Keywords: | Conductivitat elèctrica Transport biològic Proteïnes Electric conductivity Biological transport Proteins |
Issue Date: | 28-Jun-2021 |
Publisher: | Nature Publishing Group |
Abstract: | Filamentous cable bacteria display long-range electron transport, generating electrical currents over centimeter distances through a highly ordered network of fibers embedded in their cell envelope. The conductivity of these periplasmic wires is exceptionally high for a biological material, but their chemical structure and underlying electron transport mechanism remain unresolved. Here, we combine high-resolution microscopy, spectroscopy, and chemical imaging on individual cable bacterium filaments to demonstrate that the periplasmic wires consist of a conductive protein core surrounded by an insulating protein shell layer. The core proteins contain a sulfur-ligated nickel cofactor, and conductivity decreases when nickel is oxidized or selectively removed. The involvement of nickel as the active metal in biological conduction is remarkable, and suggests a hitherto unknown form of electron transport that enables efficient conduction in centimeter-long protein structures. |
Note: | Reproducció del document publicat a: https://doi.org/10.1038/s41467-021-24312-4 |
It is part of: | Nature Communications, 2021, vol. 12, num. 1 |
URI: | http://hdl.handle.net/2445/180328 |
Related resource: | https://doi.org/10.1038/s41467-021-24312-4 |
ISSN: | 2041-1723 |
Appears in Collections: | Articles publicats en revistes (Enginyeria Electrònica i Biomèdica) Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC)) Publicacions de projectes de recerca finançats per la UE |
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