Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/185257
Title: COVID-19 as a unique opportunity to unravel the link between prenatal maternal infection, brain development and neuropsychiatric disorders in offspring
Author: Ayesa-Arriola, Rosa
López-Díaz, Álvaro
Ruiz-Veguilla, Miguel
Leza, Juan Carlos
Fañanás Saura, Lourdes
Crespo-Facorro, Benedicto
Keywords: COVID-19
Malalties mentals
COVID-19
Mental illness
Issue Date: Jan-2021
Publisher: Elsevier España
Abstract: Study of the effects of prenatal maternal infection on early offspring brain development has long attracted the interest and endeavors of clinicians and neuroscientists.1 Early reports on large-scale ecological data and further birth cohort studies analyzing biomarkers in pregnancy and early life of offspring have yielded evidence that in-utero exposure to infection increases neuropsychiatric disorder risk, particularly schizophrenia and autism spectrum disorders.2, 3, 4 The main hypothesis derived from these studies is that activation of immune-inflammatory pathways during maternal infection may result in abnormal fetal brain development.5 However, such a hypothesis requires detailed testing to reveal the pathogenic and pathophysiological mechanisms behind these neurodevelopmental alterations.
Note: Versió postprint del document publicat a: https://doi.org/10.1016/j.rpsm.2020.12.003
It is part of: Revista de Psiquiatria y Salud Mental, 2021, vol. 14, num. 1, p. 1-3
URI: http://hdl.handle.net/2445/185257
Related resource: https://doi.org/10.1016/j.rpsm.2020.12.003
ISSN: 1888-9891
Appears in Collections:Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)

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