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http://hdl.handle.net/2445/189351
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DC Field | Value | Language |
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dc.contributor.author | Mercadal-Orfila, Gabriel | - |
dc.contributor.author | Font, Julia | - |
dc.contributor.author | Pons, Marta | - |
dc.contributor.author | Blasco Mascaró, Ignacio | - |
dc.contributor.author | Piqué i Clusella, Núria | - |
dc.date.accessioned | 2022-09-28T08:02:40Z | - |
dc.date.available | 2022-09-28T08:02:40Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 0954-0121 | - |
dc.identifier.uri | http://hdl.handle.net/2445/189351 | - |
dc.description.abstract | Currently, the management of comorbidities and polypharmacy in HIV-infected patients requires a coordinated action, with special focus on gender differences. Observational, cross-sectional study was conducted to study the HIV population from Menorca (Illes Balears). Adult HIV-positive individuals on antiretroviral treatment attending the pharmacy service from Hospital Mateu Orfila (Menorca) were included. In a single visit, demographical and clinical characteristics, comorbidities and cotreatments were collected. Anticholinergic burden (Drug Burden Index, DBI), drug-to-drug interactions (BOT PLUS database) and symptoms associated with HIV treatment (HIV-SI index) were assessed. A total of 223 patients were included, 68.2% men, with a median age of 53.00 (44.50-58.00) years, median BMI of 24.07, 47.73% smokers and 9.90% drug consumers. Women had more advanced stages of the disease and significantly more symptoms (cough and anxiety) versus men (p = .033 and p = .048, respectively). Moreover higher exposures to anticholinergic drugs (DBI 0.51 vs. 0.27) were reported, together with more frequency of drug-to-drug interactions (57.7% vs. 37.5%; p = .005) that increased with age. Red interactions were more frequently reported in PI (2.69%), NNRTIs (1.92%) and booster drugs (1.92%). These results support the need to implement specific measures for the management of HIV-infected women and tools to assess polypharmacy and risk of drug-to-drug interactions. Keywords: HIV infection; anticholinergic burden; anxiety; comorbidities; drug-to-drug interactions; women. | - |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Taylor and Francis | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1080/09540121.2022.2067518 | - |
dc.relation.ispartof | Aids Care-Psychological and Socio-Medical Aspects of Aids/Hiv, 2022, p. 1-10 | - |
dc.relation.uri | https://doi.org/10.1080/09540121.2022.2067518 | - |
dc.rights | cc by-nc-nd (c) Gabriel Mercadal-Orfila, et al., 2022 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.source | Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) | - |
dc.subject.classification | Infeccions per VIH | - |
dc.subject.classification | VIH (Virus) | - |
dc.subject.classification | Dones | - |
dc.subject.other | HIV infections | - |
dc.subject.other | HIV (Viruses) | - |
dc.subject.other | Women | - |
dc.title | HIV-positive women have higher prevalence of comorbidites and anticholinergic burden. Assessment of the HIV positive population from Menorca (Balearic Islands) | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 724351 | - |
dc.date.updated | 2022-09-28T08:02:40Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) |
Files in This Item:
File | Description | Size | Format | |
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724351.pdf | 1.88 MB | Adobe PDF | View/Open |
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