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Title: A prospective, randomized, triple-blind comparison of articaine and bupivacaine for maxillary infiltrations
Author: Vílchez Pérez, Miguel-Ángel
Sancho Puchades, Manuel
Valmaseda Castellón, Eduardo
Paredes García, Jordi
Berini Aytés, Leonardo
Gay Escoda, Cosme
Keywords: Maxil·lars
Anestèsia en odontologia
Anestèsia local
Anesthesia in dentistry
Local anesthesia
Issue Date: 1-Mar-2012
Publisher: Medicina Oral SL
Abstract: Objectives: To compare the clinical anesthetic efficacy of 0.5% bupivacaine and 4% articaine (both with 1:200.000 adrenaline) for anterior maxillary infiltration in healthy volunteers. Material and methods: A triple-blind split-mouth randomized clinical trial was carried out in 20 volunteers. A supraperiosteal buccal injection of 0.9 ml of either solution at the apex of the lateral incisor was done in 2 appointments separated 2 weeks apart. The following outcome variables were measured: latency time, anesthetic efficacy (dental pulp, keratinized gingiva, alveolar mucosa and upper lip mucosa and tissue) and the duration of anesthetic effect. Hemodynamic parameters were monitored during the procedure. Results: Latency time recorded was similar for both anesthetic solutions (p>0.05). No statistically significant differences were found in terms of anesthetic efficacy for dental pulp, keratinized gingiva or alveolar mucosa. Articaine had a significant higher proportion of successful anesthesia at 10 minutes after infiltration in lip mucosa and lip skin (p=0.039). The duration of anesthesia was 336 minutes for bupivacaine and 167 minutes for articaine. (p<0.001). No significant hemodynamic alterations were noted during the procedure. Conclusions: Articaine and bupivacaine exhibited similar anesthetic efficacy for maxillary infiltrations. The duration of anesthesia was longer with the bupivacaine solution, but lip anesthesia was better with articaine
Note: Reproducció del document publicat a:
It is part of: Medicina Oral, Patología Oral y Cirugia Bucal, 2012, vol. 17, num. 2, p. 325-330
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ISSN: 1698-4447
Appears in Collections:Articles publicats en revistes (Odontostomatologia)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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