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dc.contributor.authorVinardell Martínez-Hidalgo, Ma. Pilar-
dc.description.abstractIn Europe, the safety evaluation of cosmetics is based on the safety evaluation of each individual ingredient. Article 3 of the Cosmetics Regulation specifies that a cosmetic product made available on the market is to be safe for human health when used normally or under reasonably foreseeable conditions. For substances that cause some concern with respect to human health (e.g. colorants, preservatives, UV-filters), safety is evaluated at the Commission level by a scientific committee, presently called the Scientific Committee on Consumer Safety (SCCS). According to the Cosmetics Regulations, in the EU, the marketing of cosmetics products and their ingredients that have been tested on animals for most of their human health effects, including acute toxicity, is prohibited. Nevertheless, any study dating from before this prohibition took effect is accepted for the safety assessment of cosmetics ingredients. The in vitro methods reported in the dossiers summited to the SCCS are here evaluated from the published reports issued by the scientific committee of the Directorate General of Health and Consumers (DG SANCO); responsible for the safety of cosmetics ingredients. The number of studies submitted to the SCCS that do not involve animals is still low and in general the safety of cosmetics ingredients is based on in vivo studies performed before the prohibition.-
dc.format.extent7 p.-
dc.publisherUniversity College London, Faculty of Mathematical and Physical Sciences, Department of Mathematics-
dc.relation.isformatofVersió postprint del document publicat a:
dc.relation.ispartofRegulatory Toxicology and Pharmacology, 2015, vol. 71, num. 2, p. 198-204-
dc.rights(c) University College London, Faculty of Mathematical and Physical Sciences, Department of Mathematics, 2015-
dc.subject.classificationAvaluació del risc per la salut-
dc.subject.classificationExperimentació animal-
dc.subject.classificationPaïsos de la Unió Europea-
dc.subject.otherHealth risk assessment-
dc.subject.otherAnimal experimentation-
dc.subject.otherEuropean Union countries-
dc.titleThe use of non-animal alternatives in the safety evaluations of cosmetics ingredients by the Scientific Committee on Consumer Safety (SCCS)-
Appears in Collections:Articles publicats en revistes (Bioquímica i Fisiologia)

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