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Title: An algebraic topological method for multimodal brain networks comparison
Author: Simas, Tiago
Chavez, Mario
Rodriguez, P.
Díaz Guilera, Albert
Keywords: Xarxes neuronals (Neurobiologia)
Teoria de grafs
Neural networks (Neurobiology)
Graph theory
Issue Date: 6-Jul-2015
Publisher: Frontiers Media
Abstract: Understanding brain connectivity is one of the most important issues in neuroscience. Nonetheless, connectivity data can reflect either functional relationships of brain activities or anatomical connections between brain areas. Although both representations should be related, this relationship is not straightforward. We have devised a powerful method that allows different operations between networks that share the same set of nodes, by embedding them in a common metric space, enforcing transitivity to the graph topology. Here, we apply this method to construct an aggregated network from a set of functional graphs, each one from a different subject. Once this aggregated functional network is constructed, we use again our method to compare it with the structural connectivity to identify particular brain regions that differ in both modalities (anatomical and functional). Remarkably, these brain regions include functional areas that form part of the classical resting state networks. We conclude that our method -based on the comparison of the aggregated functional network- reveals some emerging features that could not be observed when the comparison is performed with the classical averaged functional network.
Note: Reproducció del document publicat a:
It is part of: Frontiers in Psychology, 2015, vol. 6, num. 904, p. 1-8
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ISSN: 1664-1078
Appears in Collections:Articles publicats en revistes (Física de la Matèria Condensada)

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