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http://hdl.handle.net/2445/68570
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DC Field | Value | Language |
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dc.contributor.author | Abbatecola, Angela M. | - |
dc.contributor.author | Cherubini, Antonio | - |
dc.contributor.author | Guralnik, Jack M. | - |
dc.contributor.author | Andrés Lacueva, Ma. Cristina | - |
dc.contributor.author | Ruggiero, Carmelinda | - |
dc.contributor.author | Maggio, Marcello | - |
dc.contributor.author | Bandinelli, Stefania | - |
dc.contributor.author | Paolisso, Giuseppe | - |
dc.contributor.author | Ferrucci, Luigi | - |
dc.date.accessioned | 2015-12-22T16:00:37Z | - |
dc.date.available | 2015-12-22T16:00:37Z | - |
dc.date.issued | 2009-02 | - |
dc.identifier.issn | 1549-1684 | - |
dc.identifier.uri | http://hdl.handle.net/2445/68570 | - |
dc.description.abstract | Due to supporting evidence that dietary patterns may have a significant role in the maintenance of good physical performance with aging, we tested whether plasma fatty acids, saturated fatty acids (SFA), and polyunsaturated (PUFA) fatty acids are cross-sectionally associated with different physical performance and predict changes in physical performance over a 3-year period. Data were from the InCHIANTI study, a population-based study of older Italians. Plasma fatty acids were measured at enrollment (1998-2000), and outcome variables, Summary Physical Performance Battery (SPPB), and time to walk 7 meters (m) were measured at enrollment and after 3 years (2001-2004). At enrollment, 330 participants had significantly impaired lower extremity performance (defined as a SPPB score < or = 9). Adjusting for age, participants with a SPPB score > 9 had higher levels of total PUFA, n-3 PUFA, and n-6 PUFA, while significantly lower levels of SFA than those with a SPPB score < 9. Baseline SPPB scores were also associated with n-3 PUFA (beta = 0.148, p = 0.031), whereas the 7-m walk time was associated with total PUFA (beta = - 0.068, p = 0.008), after adjusting for potential confounders. Of the 884 participants with a SPPB score > 9 at baseline, 114 (12.9%) developed impaired lower extremity performance (SPPB < or = 9). In fully adjusted logistic models, baseline n-3 PUFA levels were inversely related to the risk of developing a decline in SPPB to < or = 9 (odds ratio [OR] = 0.21; 95% confidence interval [CI] = 0.08-0.53), while the n-6/n-3 ratio was associated with a higher risk of SPPB decline to < or = 9 (OR = 5.23; 95% CI = 2.02-13.51). In multivariate regression models, the n-6/n-3 ratio was associated with a longer time to walk 7 m (beta = 0.396, p = 0.037). n-3 PUFA plasma levels, which most likely reflect dietary intake, seem to protect against accelerated decline of physical performance. A higher n-6/n-3 ratio was associated with higher risk of developing poor physical performance and slower walking speed. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Mary Ann Liebert, Inc. | - |
dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.1089/rej.2008.0799 | - |
dc.relation.ispartof | Rejuvenation Research, 2009, vol. 12, num. 1, p. 25-32 | - |
dc.relation.uri | http://dx.doi.org/10.1089/rej.2008.0799 | - |
dc.rights | (c) Mary Ann Liebert, Inc., 2009 | - |
dc.source | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) | - |
dc.subject.classification | Envelliment | - |
dc.subject.classification | Àcids grassos insaturats | - |
dc.subject.classification | Motricitat | - |
dc.subject.classification | Condició física | - |
dc.subject.other | Aging | - |
dc.subject.other | Unsaturated fatty acids | - |
dc.subject.other | Motor ability | - |
dc.subject.other | Physical fitness | - |
dc.title | Plasma polyunsaturated fatty acids and age-related physical performance decline | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 567717 | - |
dc.date.updated | 2015-12-22T16:00:37Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 19196012 | - |
Appears in Collections: | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) |
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File | Description | Size | Format | |
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567717.pdf | 81.68 kB | Adobe PDF | View/Open |
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