Dipòsit Digital de la Universitat de Barcelona

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El Dipòsit Digital de la Universitat de Barcelona és el repositori institucional que conté en format digital els materials derivats de l'activitat docent, investigadora i institucional de la comunitat universitària.

Enviaments recents

Rationale and design of the NATURCEL registry: Study of the NATURal history and the epidemiological, clinical, diagnostic and therapeutic aspects of CoELiac disease and noncoeliac enteropathies.
(Elsevier, 2026-06-01) Planella, Montserrat; Salas, Azucena; Videla, Sebastià; Loras, Carme; Esteve i Comas, Maria; Martín Cardona, Albert; Ibáñez Sanz, Gemma; Sudrià‑Lopez, Emma; Arau, Beatriz; Carballal, Sabela; García Puig, Roger; Carrasco García, Anna; Villar Balboa, Iván; Ibarra, Montserrat; Ferrer Cassadó, Carme; Fonolleda, Mireia
Coeliac disease is a chronic immune-mediated enteropathy triggered by gluten intake, which affects the small intestine in genetically susceptible individuals (HLA-DQ2 and/or HLA-DQ8). This disease, which occurs in both children and adults, is among the most common genetically determined disorders in Western countries. It is characterized by the presence of very varied and often nonspecific clinical manifestations (primarily digestive symptoms and signs of intestinal malabsorption), as well as the presence of specific antibodies (tissue transglutaminase and endomysium) and enteropathy. Currently, the only treatment for coeliac disease is a strict gluten-free diet for life. The main objective of the NATURCEL (NATURal history, epidemiological, clinical, diagnostic and therapeutic aspects of CoELiac disease and noncoeliac enteropathies) registry is to collect selected variables on different aspects of the disease (epidemiological, clinical, genetic, immunological, etc.) for a subsequent shared analysis for scientific and translational purposes.
Predictive epigenetic biomarkers of successful weight-loss intervention in pre-pubertal children with obesity
(BioMed Central, 2026-05-29) Palmieri, Flavio; Castellano Escuder, Pol; Parra-Vargas, Marcela; Leal Witt, María Jesús; Ramon-Krauel, Marta; Lerin, Carles; Perera Lluna, Alexandre; Jiménez-Chillarón, J.C.
Childhood obesity represents a major public health challenge, increasing long-term risks such as type 2 diabetes and cardiovascular disease. Lifestyle interventions in prepubertal children are often more effective, but individual responses can vary, highlighting the need for predictive biomarkers to personalize treatment. This study investigated DNA methylation profiles in prepubertal children living with obesity to identify possible epigenetic markers that could predict the success of weight loss interventions. We analyzed a cohort of 26 children who underwent a six-month lifestyle intervention focused on dietary modifications. From 214 differentially methylated CpG sites between high and low responders, we narrowed these to eight key markers. These markers were used to develop a predictive model with a precision 84% in classifying children based on their BMI normalized to changes in the z-score of the age. CpGs were found in genes such as GSDMD, GFRA1 and NRP2, all linked to pathways involved in inflammation, metabolic regulation, and lipid metabolism, which are crucial in the development of obesity. The results suggest that DNA methylation signatures can predict weight loss responses in prepubertal children, offering a novel approach to early-stage obesity intervention. These findings hold promise for the development of personalized treatment strategies in pediatric obesity. However, larger and more diverse cohort studies are needed to confirm the generalizability of these markers and refine the predictive model for broader clinical use.
Creación de un negocio deportivo: estudio de gimnasia infantil y actividades para adultos
(2026) Reut, Maryia; Triadó i Ivern, Xavier Ma.
A continuación se presenta un trabajo de investigación empresarial en el que se analiza la viabilidad de creación de un centro deportivo en Barcelona cuyo target principal está enfocado a familias, niños y adultos. Se observa –a través del análisis del mercado en este sector, un estudio de la competencia y la realización de encuestas a potenciales usuarios– una importante demanda en actividades físicas infantiles, así como un creciente interés de las familias por un modelo en el que converjan actividades simultáneas para niños y adultos. Esta conclusión, apoyada con un estudio financiero, muestra la viabilidad de la iniciativa y presenta potencialidad de negocio en el mercado local.
Search engine visibility of university AI content: an analysis of thirty institutions from three countries
(Emerald Publishing, 2025-11-26) Vállez, Mari, 1968-; Alcaraz Martínez, Rubén; Lopezosa, Carlos
Purpose: This study aims to investigate the search engine visibility of web content published by universities about artificial intelligence (AI), with the aim of evaluating their digital communication and dissemination strategies. The analysis focuses on the highest-ranking AI-related content found on Google, based on the domains of 30 universities from three countries. Web analysis tools are used to measure the visibility and impact of this content, enabling the identification of patterns and areas for improvement in the digital dissemination strategies of these academic institutions. Design/methodology/approach: To carry out this task, the first step was to determine the web visibility of the universities studied using SEMrush for the terms Artificial Intelligence/Generative Artificial Intelligence, OpenAI, ChatGPT/GPT. This quantitative analysis was complemented by a mixed-method approach, focusing on the analysis and evaluation of specific ranking factors present in the highest-ranking pages, with the aim of identifying best practices. Findings: The results confirm that while the universities analysed are active content creators, they do not achieve notable Web visibility when searching for information on AI or related keywords using search engines. Among the 30 universities studied, only three stand out in terms of the number of ranked webpages. Originality/value: While research on SEO has been conducted across various fields, no studies have yet explored the intersection of university Web visibility and searches for information on artificial intelligence in search engines. The key contributions that set this study apart are, firstly, its global perspective on the web visibility of AI-related content produced by universities and, secondly, its value-added recommendations for enhancing their online presence.
Understanding the Thermodynamic Properties of the Elastocaloric Effect Through Experimentation and Modelling
(Springer, 2016-11-28) Tusek, J.; Engelbrecht, Kurt; Mañosa, Lluís; Vives i Santa-Eulàlia, Eduard; Pryds, Nini
This paper presents direct and indirect methods for studying the elastocaloric effect (eCE) in shape memory materials and its comparison. The eCE can be characterized by the adiabatic temperature change or the isothermal entropy change (both as a function of applied stress/strain). To get these quantities, the evaluation of the eCE can be done using either direct methods, where one measures (adiabatic) temperature changes or indirect methods where one can measure the stress–strain–temperature characteristics of the materials and from these deduce the adiabatic temperature and isothermal entropy changes. The former can be done using the basic thermodynamic relations, i.e. Maxwell relation and Clausius–Clapeyron equation. This paper further presents basic thermodynamic properties of shape memory materials, such as the adiabatic temperature change, isothermal entropy change and total entropy–temperature diagrams (all as a function of temperature and applied stress/strain) of two groups of materials (Ni–Ti and Cu–Zn–Al alloys) obtained using indirect methods through phenomenological modelling and Maxwell relation. In the last part of the paper, the basic definition of the efficiency of the elastocaloric thermodynamic cycle (coefficient of performance) is defined and discussed.