Dipòsit Digital de la Universitat de Barcelona

El Dipòsit Digital de la Universitat de Barcelona és el repositori institucional que conté en format digital els materials derivats de l'activitat docent, investigadora i institucional de la comunitat universitària.
Enviaments recents
- LlibreEl Modernisme i les flors : de la natura a l'arquitectura(Barcelona : Diputació de Barcelona, 2019) López, Fàtima; Saliné i Perich, Marta; López, Fàtima; Saliné i Perich, Marta; Barcelona (Catalunya : Província). Àrea de CulturaEntre finals del segle XIX i començaments del segle XX, la natura, i en particular la flora, va ser la gran musa i font d'inspiració d'arquitectes i artistes. Aquest catàleg recull el contingut de l'exposició, que reuneix obres de diversos museus de la Xarxa de Museus Locals de la Diputació de Barcelona, ens apropa al Modernisme a través de la natura i de les arts aplicades en la natura, entre les quals el simbolisme de les flors va tenir un paper destacat.
Article
High inappropriate red blood cell transfusion rate despite low overall use: a real-world multicenter study in 43 Spanish hospitals(Frontiers Media, 2026-05-14) Tamayo Velasco, Álvaro; Llau Pitarch, Juan Vicente; Colomina Soler, M. J. (María José); De la Varga Martínez, Olga; Navarro Pérez, Rosalía; López Herrero, Rocío; Almoguera Fernández, Jorge; Alonso Fernández, Marta; Artiaga-Candia, María; Becerra-Bolaños, Angel; Bugueño, Natalia; Casasempere Sanus, Alma; Contreras López, Laura; Heredia Rodríguez, María; de la Fuente Graciani, Ignacio; De la Rosa-Estadella, Marta; De la Torre Riveiro, Iria; Del Val Peciña, Elena; Delgado Martí, Carla; Edo Cebollada, Laura; Fernández Fernández, Ricardo; Fernández Rodríguez, Jorge; Ferrer Gómez, Carolina; Giné Servén, Marta; González Pereira, Almudena; Guereca Gala, Ane; Herrera Soto, Aurora; Infantes Morales, Marta E.; Marcos Vidal, José Miguel; Illodo Miramontes, Gustavo; Martínez López, Adrián; Martínez Ruiz, Alberto; Martínez Rafael, Beatriz; Matute González, A.; Pariente Juste, Laura; Pérez González, Sonia; Gómez Pesquera, Estefania; Renedo Fernández, Ainhoa; Rodríguez Álvarez, A.A.; Sánchez Rodríguez, Iván; del Aranzazú Rodríguez-Conesa, María; Sánchez González, Cristina; Tobar Gonzalo, Cristina; Varela Rodríguez, Lorena; Veloso de Sousa, Rita; Muñoz Moreno, María Fe; García-Sánchez, José; Rocha García, Felipe; González Montes, Pablo; Cid Boo, Patricia; Escudero Gómez, Gabriel; Romero García, Nekane; Cots, Ana; Peñarrubia Ponce, Maria Jesus; Hornero, Roberto; Santamaría-Vázquez, Eduardo; Poves Álvarez, Rodrigo; Tamayo, Eduardo; Varela Duran, Marina; Badenes, RafaelBackground: Since their implementation in Spain, adherence of hospitals to Patient Blood Management (PBM) programs has been variable, potentially influencing transfusion practices. This study aimed to evaluate, in a real-world surgical setting, the frequency and appropriateness of red blood cell (RBC) transfusion. Methods: A prospective multicenter study in 43 Spanish hospitals including surgical patients. Transfusion appropriateness was evaluated using evidence-based criteria based on hemoglobin thresholds and clinical conditions such as cardiovascular disease, acute hemorrhage, or high comorbidity burden. Statistical analyses identified factors associated with transfusion practices. Results: The overall perioperative RBC transfusion rate was 9.7%, with the highest rates in cardiac (52.9%), vascular (17.9%), and orthopedic (12.3%) surgeries. RBC transfusion was associated with older patients with comorbidities, lower preoperative hemoglobin, higher ASA score and worse surgical meters and postoperative outcomes. Transfused patients showed significantly lower 60-day survival. Critically, 43% of transfusions were inappropriate, while transfusion omission (1.9%) may represent a clinical concern that warrants further investigation. Inappropriate transfusion was more frequent in older comorbidity patients according to Charlson Comorbidity Index in urgent surgery. In multivariable analysis, age was a factor associated with inappropriate transfusion, by cons, surgical blood loss was the main protective factor against inappropriate transfusion. Conclusion: As far as we know, this is the first Spanish multicenter study evaluating transfusion appropriateness in surgical scenario. Despite a lower overall transfusion rate than international figures, nearly half of transfusions were inappropriate and transfusion omission, also represents a real clinical concern. Implementation of decision-support tools and strengthened PBM protocols are needed to address factors associated with inappropriate transfusion, such as age, and to optimize patient safety and resource use.Treball de fi de grau
Comparison and adaptation of Freinet's methodology to TBLT(2026-06-16) Agulló Ponsirenas, Elisabet; Gilabert Guerrero, Roger[eng] This paper aims to analyze, and compare Célestin Freinet’s methodology and Task-Based Language Teaching. Consequently, proposing an adaptation of the Freinetian approach into TBLT methodology. The research is mainly focused around three books written by Célestin Freinet (1973; 1996; 2005), and one written by Michael Long (2015). Freinet’s methodology pursues natural acquisition connected to students’ needs, and interests. It fosters motivation through experimentation and communication between learners. TBLT is developed around students’ communicational needs and implemented through meaningful tasks. The paper concludes that both approaches establish a similar philosophical background from which distinctive methodological tools are developed. Thus, Freinetian adaptation into TBLT is plausible and highly beneficial for compulsory education. Generally, the adaptation enhances students’ motivation through TBLT’s techniques.Article
Brain Metabolite Levels in the Post-Acute Stage of Anti-NMDA Receptor Encephalitis and Schizophrenia: A Longitudinal Case-Control Study(Elsevier B.V., 2026-07-15) Fortea, Adriana; Ortuño, María; Masias, Mireia; Guasp, Mar; Serna, Elena de la, 1978-; Armangué, Thaís; Baeza, Inmaculada, 1970-; Borràs, Roger; Prades-Senovilla, Laia; Rosa Justicia, Mireia; Stein, Heike; Martínez Heras, Eloy; Compte Braquets, Albert; Llufriu Duran, Sara; Dalmau Obrador, Josep; Castro Fornieles, Josefina; Sugranyes Ernest, GiselaBackground: In vivo assessment of glutamatergic metabolites in patients with anti-NMDA receptor (anti-NMDAR) encephalitis compared with schizophrenia may help increase understanding of the pathophysiology of both conditions. Methods: This 24-month prospective case-control study included participants ages 12 to 60 years with anti-NMDAR encephalitis during the post-acute stage and age- and sex-matched individuals with schizophrenia and healthy control participants (HCs). Single-voxel magnetic resonance spectroscopy was used to estimate brain concentrations of glutamatergic metabolites, myo-inositol, and N-acetylaspartate+N-acetylaspartylglutamate (tNAA) in the left dorsomedial prefrontal region (dmPF) and medial temporal lobe. The effect of group and time on metabolite levels and the relationship between metabolite levels and psychiatric and cognitive features were tested with multilevel linear mixed models. Results: Thirty-two participants with anti-NMDAR encephalitis (84% women), 27 participants with schizophrenia (63% women), and 36 HCs (72% women) were included. In the dmPF, levels of glutamate and glutamate+glutamine were significantly lower in patients with anti-NMDAR encephalitis than in participants with schizophrenia (Cohen's d = -0.87 and d = -0.80, respectively) and HCs (d = -0.73 and d = -0.71). Myo-inositol levels were significantly higher in both participants with anti-NMDAR encephalitis (d = 0.91) and patients with schizophrenia (d = 1.07) than in HCs. Group differences remained stable over time. Metabolite levels were not associated with psychiatric or cognitive symptoms. Conclusions: This is the first report of hypoglutamatergia in the left dmPF in anti-NMDAR encephalitis and of increased levels of myo-inositol in both anti-NMDAR encephalitis and schizophrenia. The findings suggest persistent alterations in glutamatergic neurotransmission during the post-acute stage of anti-NMDAR encephalitis and overlapping neuroinflammatory processes between anti-NMDAR encephalitis and schizophrenia.Article
Psychometric validation of the Cannabis Withdrawal Checklist in a Spanish sample with cannabis use disorder(Frontiers Media, 2026-05-15) Saura, Judith; Feliu, Ariadna; Enríquez-Mestre, Marta; Roca Tutusaus, Xavier; Ballbè i Gibernau, Montse; Fu Balboa, Marcela; Segura García, Lidia; Fernández Muñoz, Esteve; Martínez Martínez, CristinaIntroduction: Cannabis is used globally. In Spain, it is often used in combination with tobacco, which may exacerbate withdrawal severity. Currently, no validated instrument exists to assess cannabis withdrawal symptoms in Spanish populations. This study aimed to validate the 15-item Cannabis (Marijuana) Withdrawal Checklist (CWC) for Spanish-speaking individuals who co-use cannabis and tobacco. Materials and methods: This psychometric validation study was nested within a multicenter longitudinal project conducted across 10 substance use treatment programs in Catalonia (Spain). The CWC was forward- and back-translated following COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) recommendations. Internal consistency, construct validity, and sensitivity to change over time were assessed using Cronbach’s alpha, exploratory factor analysis (EFA), and mixed-effects analysis. Data from 82 participants were used to conduct the validation. Results: The adapted CWC demonstrated high internal consistency (Cronbach’s α = 0.918 at baseline; 0.885 at 2 weeks of treatment). EFA supported a unidimensional structure explaining approximately 60% of the variance. Although symptom severity did not significantly change over follow-up, withdrawal intensity was positively associated with the level of cannabis use. The scale effectively captured clinically relevant symptoms such as irritability, craving, and sleep difficulties. Conclusion: The Spanish CWC showed strong reliability and acceptable psychometric properties, supporting its use for assessing cannabis withdrawal symptoms in Spanish-speaking adults, particularly those who co-use tobacco products. The scale may be valuable in both research and clinical settings, particularly for monitoring withdrawal during treatment interventions. Further validation using larger, more diverse samples is warranted.







