Dipòsit Digital de la Universitat de Barcelona
El Dipòsit Digital de la Universitat de Barcelona és el repositori institucional que conté en format digital els materials derivats de l'activitat docent, investigadora i institucional de la comunitat universitària.
Enviaments recents
ArticleAlterations in the masticatory system in patients with amyotrophic lateral sclerosis(MRE Press - Medical Research Exploration, 2018-03-30) Riera-Punet, Nina; Martínez Gomis, Jordi; Paipa, Andres Julian; Povedano Panades, Mónica; Peraire, MaríaAIMS: To determine the effect of amyotrophic lateral sclerosis (ALS) on aspects of masticatory function and to assess the relationship between ALS and the prevalence of traumatic mucosal lesions caused by oral self-injury. METHODS: A total of 153 ALS patients and 23 control subjects participated in this cross-sectional study. Clinical characteristics including site of onset, medication, type of feeding, and use of noninvasive mechanical ventilation were recorded. The Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) protocol and a specific questionnaire to assess aspects of masticatory dysfunction and frequency of self-injury of the oral mucosa were applied to all participants. Maximum mandibular range of motion, maximum bite force, and maximum finger-thumb grip force were determined and tested with Mann Whitney, Kruskal-Wallis, or chi-square tests. P < .05 was considered significant. RESULTS: Maximum unassisted and assisted mouth opening, protrusion, left laterotrusion, and finger-thumb grip force were significantly reduced in both spinal- (n = 102) and bulbar-onset (n = 40) patients compared to the control group; however, bite force was reduced only in bulbar-onset patients. ALS patients with tube feeding (n = 16) had the greatest reduction in maximum bite force and mandibular opening. There was no relationship between TMD and ALS. Oral self-injury due to biting was more frequent in the ALS group (29.9%) than in the control group (8.7%) and in the bulbar-onset group (55.0%) compared to the spinal- (20.8%) and respiratory-onset (18.2%) groups. Of the ALS patients in the study, 10% sought dental treatment related to the condition. CONCLUSION: The ALS patients in this study had a reduction in finger-thumb grip force that was twice as great as the reduction in bite force. The maximum range of mandibular movement was also reduced, especially in bulbar-onset patients. ALS patients did not have a higher prevalence of TMD but did have more traumatic mucosal injury than controls. The dentist should be an integral part of the multidisciplinary team to manage ALS patients.- ArticleEmilio Urberuaga: Un tipo con suerte que se lo ha pasado muy bien(Editorial Torre de Papel, 2022-01) Obiols Suari, Núria; Martínez Gómez, EduardoEntrevista con el autor e ilustrador Emilio Uberuaga en la que se tratan aspectos variados de su trabajo, recientes y antiguos, así como el análisis de algunas realidades de la literatura infantil.
- ArticleSynthesis of the Adenosine A2A Receptor Fluorescent Agonist MRS5424(Bio-protocol LLC, 2014-03-20) Jacobson, Kenneth A.; Ciruela Alférez, FranciscoMRS5424 is a functional fluorescent agonist for the adenosine A2A receptor (A2AR) in which the fluorescent dye Alexa Fluor 532 is covalently attached to the A2AR agonist 2-[[2-[4-[2-(2-aminoethyl)-aminocarbonyl]ethyl]phenyl]ethylamino]-5'-N-ethylcarboxamidoadenosine (APEC). This easy-to-synthesize new A2AR fluorescent ligand was shown to be extremely useful for determining the binding kinetic constants of A2AR in a real-time mode (Fernandez-Duenas et al., 2012). In addition, this fluorescent A2AR ligand is compatible with ligand-receptor interaction studies using fluorescent plate readers. Finally, it is important to mention that even though the sensitivity of this A2AR fluorescent ligand may not be as high as that observed for the marketed A2AR radioactive compounds, the use of such fluorescent derivative may have some advantages over radioactive probes, for example its safe delivery, manipulation and disposal, the short signal acquisition times, the feasibility to automate and to miniaturize, and finally its cost.
- ArticleRessenya bibliogràfica de Poema pedagògic: Un referent poètic tan imprescindible com evocador: Antón Semiónovich Makárenko(Editorial Graó, 2021-10) Obiols Suari, NúriaRessenya sobre l'obra Poema Pedagògic d'A.S. Makarenko
- ArticleGusti o el arte de improvisar(Editorial Torre de Papel, 2021-11) Obiols Suari, Núria; Martínez Gómez, EduardoEntrevista con el ilustrador Gusti en la que se consideran estilos de ilustración, además del recorrido por su extensa obra.