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Title: Impact of psychosocial factors on cardiovascular morbimortality: a prospective cohort study
Author: Mejía-Lancheros, Cília
Estruch Riba, Ramon
Martínez-González, Miguel Ángel, 1957-
Salas Salvadó, Jordi
Castañer, Olga
Corella Piquer, Dolores
Arós, Fernando
Gómez Gracia, Enrique
Fiol Sala, Miguel
Lapetra, José
Serra Majem, Lluís
Pintó Sala, Xavier
Ros Rahola, Emilio
Díez Espino, Javier
Basora, Josep
Sorlí, José V.
Lamuela Raventós, Rosa Ma.
Ruiz-Gutiérrez, Valentina
Muñoz, Miguel Ángel
PREDIMED Study Investigators
Keywords: Morbiditat
Malalties cardiovasculars
Factors de risc en les malalties
Estudi de casos
Assaigs clínics
Cardiovascular diseases
Risk factors in diseases
Case studies
Clinical trials
Issue Date: 3-Oct-2014
Publisher: BioMed Central
Abstract: Abstract BACKGROUND: Whilst it is well known that psychosocial determinants may contribute to cardiovascular diseases (CVD), data from specific groups are scarce. The present study aims to determine the contribution of psychosocial determinants in increasing the risk of cardiovascular events (myocardial infarction and stroke), and death from CVD, in a high risk adult population. METHODS: Longitudinal prospective study of 7263 patients (57.5% women), mean age 67.0 (SD 6.2) free from CVD but at high risk, with a median follow-up of 4.8 years (from October 2003 to December 2010). The Hazard Ratios (HRs) of cardiovascular events (myocardial infarction, stroke, and death from cardiovascular causes) related to educational attainment, diagnosed depression (based on medical records), and low social support (number of people living in the household) were estimated by multivariate Cox regression models. RESULTS: Stroke incidence was associated with low educational level in the whole population (HR: 1.83, 95% CI: 1.09-3.09), and especially in men (HR: 2.11, 95% CI 1.09-4.06). Myocardial infarction and CVD mortality were not associated with any of the psychosocial factors considered. CONCLUSION: Adults with low educational level had a higher risk of stroke. Depression and low social support were not associated with CVD incidence. TRIAL REGISTRATION: Clinical trial registration information unique identifier: ISRCTN35739639.
Note: Reproducció del document publicat a:
It is part of: BMC Cardiovascular Disorders, 2014, vol. 14, num. 135, p. 1-9
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ISSN: 1471-2261
Appears in Collections:Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Medicina)
Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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