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Title: | The treatment of oral leukoplakia with the CO2 laser: A retrospective study of 65 patients |
Author: | Mogedas-Vegara, Alfonso Hueto-Madrid, Juan-Antonio Chimenos Küstner, Eduardo Bescós-Atín, Coro |
Keywords: | Estomatologia Malalties de la boca Virus Boca Làsers Diòxid de carboni Estudi de casos Oral medicine Mouth diseases Viruses Mouth Lasers Carbon dioxide Case studies |
Issue Date: | Jun-2015 |
Publisher: | Elsevier |
Abstract: | The use of CO2 laser has become a routine procedure for the treatment of oral leukoplakia. In this retrospective study, we evaluated 65 patients with oral leukoplakia treated with CO2 laser vaporization. The main location was the tongue (n ¼ 21/65, 32.3%). The initial biopsy showed mild/moderate dysplasia in almost half the patients (n ¼ 29, 44.6%) and hyperplasia without dysplasia in around a third of the patients (n ¼ 21, 32.3%). The recurrence and malignant transformation rates were 33.8% (n ¼ 22) and 15.4% (n ¼ 10), respectively. The follow-up mean (standard deviation) was 15.0 (10.6) months. The procedure-related complications rate was 7.7% (n ¼ 5). The KaplaneMeier curves for time to recurrence showed differences only for gingiva lesions compared to tongue lesions (log rank, p ¼ 0.032). Malignant leukoplakia transformation is independent of treatment, although it seems advisable to treat leukoplakia with or without dysplasia. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1016/j.jcms.2015.03.011 |
It is part of: | Journal of Cranio-Maxillofacial Surgery, 2015, vol. 43, num. 5, p. 677-681 |
URI: | http://hdl.handle.net/2445/112586 |
Related resource: | https://doi.org/10.1016/j.jcms.2015.03.011 |
ISSN: | 1010-5182 |
Appears in Collections: | Articles publicats en revistes (Odontoestomatologia) |
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