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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/114162
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dc.contributor.authorGamba, Ilaria-
dc.contributor.authorSalvadó, Iria-
dc.contributor.authorBrissos, Rosa F.-
dc.contributor.authorGámez Enamorado, Patrick-
dc.contributor.authorBrea, José-
dc.contributor.authorLoza, María Isabel-
dc.contributor.authorVázquez, M. Eugenio-
dc.contributor.authorVázquez López, Miguel-
dc.date.accessioned2017-07-21T07:23:43Z-
dc.date.available2017-07-21T07:23:43Z-
dc.date.issued2016-01-21-
dc.identifier.issn1359-7345-
dc.identifier.urihttp://hdl.handle.net/2445/114162-
dc.description.abstractWe demonstrate the application of solid-phase peptide synthesis methods for the straightforward assembly of polynuclear Ir(III) organometallopeptides, and show that their oligoarginine derivatives exhibit high DNA binding affinity, sequence selectivity, and high cytotoxicity towards a set of cancer cell lines.-
dc.format.extent4 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherRoyal Society of Chemistry-
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1039/C5CC07619F-
dc.relation.ispartofChemical Communications, 2016, vol. 52, num. 6, p. 1234-1237-
dc.relation.urihttps://doi.org/10.1039/C5CC07619F-
dc.rights(c) Gamba, Ilaria et al., 2016-
dc.sourceArticles publicats en revistes (Química Inorgànica i Orgànica)-
dc.subject.classificationSíntesi de pèptids-
dc.subject.classificationFísica de l'estat sòlid-
dc.subject.classificationADN-
dc.subject.classificationCàncer-
dc.subject.otherPeptide synthesis-
dc.subject.otherSolid state physics-
dc.subject.otherDNA-
dc.subject.otherCancer-
dc.titleHigh-affinity sequence-selective DNA binding by iridium(III) polypyridyl organometallopeptides-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/acceptedVersion-
dc.identifier.idgrec656122-
dc.date.updated2017-07-21T07:23:43Z-
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/FP7/340055/EU//METBIOCAT-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid26611126-
Appears in Collections:Articles publicats en revistes (Química Inorgànica i Orgànica)

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