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http://hdl.handle.net/2445/124213
Title: | Reproducibility of optical coherence tomography airway imaging |
Author: | Kirby, Miranda Ohtani, Keishi Nickens, Taylor Lopez Lisbona, Rosa Maria Lee, Anthony M. D. Shaipanich, Tawimas Lane, Pierre Macaulay, Calum Lam, Stephen Coxson, Harvey O. |
Keywords: | Òptica fisiològica Biotecnologia Physiological optics Biotechnology |
Issue Date: | 1-Nov-2015 |
Publisher: | OSA Publishing |
Abstract: | Optical coherence tomography (OCT) is a promising imaging technique to evaluate small airway remodeling. However, the short-term insertion-reinsertion reproducibility of OCT for evaluating the same bronchial pathway has yet to be established. We evaluated 74 OCT data sets from 38 current or former smokers twice within a single imaging session. Although the overall insertion-reinsertion airway wall thickness (WT) measurement coefficient of variation (CV) was moderate at 12%, much of the variability between repeat imaging was attributed to the observer; CV for repeated measurements of the same airway (intra-observer CV) was 9%. Therefore, reproducibility may be improved by introduction of automated analysis approaches suggesting that OCT has potential to be an in-vivo method for evaluating airway remodeling in future longitudinal and intervention studies. (C) 2015 Optical Society of America |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.1364/BOE.6.004365 |
It is part of: | Biomedical Optics Express, 2015, vol. 6, num. 11, p. 4365-4377 |
URI: | http://hdl.handle.net/2445/124213 |
Related resource: | http://dx.doi.org/10.1364/BOE.6.004365 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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File | Description | Size | Format | |
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KirbyM.pdf | 1.78 MB | Adobe PDF | View/Open |
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