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http://hdl.handle.net/2445/127700
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DC Field | Value | Language |
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dc.contributor.author | Solé Arjó, Daniel | - |
dc.contributor.author | Pérez Janer, Ferran | - |
dc.contributor.author | Mancuso, Raffaella | - |
dc.date.accessioned | 2019-01-29T12:04:46Z | - |
dc.date.available | 2019-01-29T12:04:46Z | - |
dc.date.issued | 2015-02-10 | - |
dc.identifier.issn | 0947-6539 | - |
dc.identifier.uri | http://hdl.handle.net/2445/127700 | - |
dc.description.abstract | A new strategy for the synthesis of tetrahydroisoquinolines based on the Pd(0)-catalyzed intramolecular α-arylation of sulfones is reported. The combination of this Pd-catalyzed reaction with intermolecular Michael and aza-Michael reactions allows the development of two- and three-step domino processes to synthesize diversely functionalized scaffolds from readily available starting materials. KEYWORDS: arylation; domino reactions; nitrogen heterocycles; palladium; sulfones | - |
dc.format.extent | 5 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Wiley-VCH | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1002/chem.201406305 | - |
dc.relation.ispartof | Chemistry-A European Journal, 2015, vol. 21, num. 12, p. 4580-4584 | - |
dc.relation.uri | https://doi.org/10.1002/chem.201406305 | - |
dc.rights | (c) Wiley-VCH, 2015 | - |
dc.source | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) | - |
dc.subject.classification | Compostos heterocíclics | - |
dc.subject.classification | Compostos de nitrogen | - |
dc.subject.classification | Compostos de sofre | - |
dc.subject.classification | Pal·ladi (Element químic) | - |
dc.subject.classification | Síntesi orgànica | - |
dc.subject.other | Heterocyclic compounds | - |
dc.subject.other | Nitrogen compounds | - |
dc.subject.other | Sulfur compounds | - |
dc.subject.other | Palladium | - |
dc.subject.other | Organic synthesis | - |
dc.title | Pd0-Catalyzed Intramoleculara-Arylation of Sulfones: Domino Reactions in the Synthesis of Functionalized Tetrahydroisoquinolines | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 649173 | - |
dc.date.updated | 2019-01-29T12:04:46Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 25677083 | - |
Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
File | Description | Size | Format | |
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649173.pdf | 373.52 kB | Adobe PDF | View/Open |
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