Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/129477
Title: | Diastereoselective and catalytic α-alkylation of chiral N-acyl thiazolidinethiones with stable carbocationic salts |
Author: | Kennington, Stuart C. D. Ferré, Laura Romo Fernández, Juan Manuel Romea, Pedro Urpí Tubella, Fèlix Font Bardia, Ma. Mercedes |
Keywords: | Catàlisi Níquel Quiralitat Catalysis Nickel Chirality |
Issue Date: | 15-Jun-2017 |
Publisher: | American Chemical Society |
Abstract: | Direct nickel-catalyzed alkylation of chiral N-acyl-4-isopropyl-1,3-thiazolidine-2-thiones using a commercially available nickel(II) complex, (Me3P)2NiCl2, has been developed for tropylium and trityl tetrafluoroborate salts. The reaction provides a single diastereomer of the corresponding adducts in good to high yields, which, in turn, can be easily converted into a wide array of enantiomerically pure compounds that are difficult to obtain by other asymmetric procedures. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1021/acs.joc.7b00657 |
It is part of: | Journal of Organic Chemistry, 2017, vol. 82, num. 12, p. 6426-6433 |
URI: | http://hdl.handle.net/2445/129477 |
Related resource: | https://doi.org/10.1021/acs.joc.7b00657 |
ISSN: | 0022-3263 |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
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672779.pdf | 521.7 kB | Adobe PDF | View/Open |
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