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http://hdl.handle.net/2445/132010
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DC Field | Value | Language |
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dc.contributor.author | Alcover García, Juan | - |
dc.contributor.author | Filella Pla, Xavier | - |
dc.contributor.author | Luque Gálvez, Ma. Pilar | - |
dc.contributor.author | Molina, Rafael (Molina Porto) | - |
dc.contributor.author | Izquierdo Reyes, Laura | - |
dc.contributor.author | Augé Fradera, Josep Maria | - |
dc.contributor.author | Alcaraz Asensio, Antonio | - |
dc.date.accessioned | 2019-04-10T18:10:16Z | - |
dc.date.available | 2019-04-10T18:10:16Z | - |
dc.date.issued | 2010-10 | - |
dc.identifier.issn | 0250-7005 | - |
dc.identifier.uri | http://hdl.handle.net/2445/132010 | - |
dc.description.abstract | AIM: The usefulness of interleukin 6 (IL-6) and its soluble receptor IL-6sR in the prediction of the biochemical recurrence was evaluated in patients with prostate cancer treated with radical prostatectomy. PATIENTS AND METHODS: IL-6 and sIL-6R serum levels were measured in 96 patients with prostate cancer. RESULTS: Using the log-rank test, it was evident that patients with preoperative serum levels of IL-6 higher than 1.2 pg/ml had a significantly increased probability of biochemical recurrence (p=0.031). We also observed that the Gleason score was associated with the risk of progression (p=0.033), but no relation was observed with TNM classification, PSA, % free PSA or sIL-6R. In a multivariate analysis, only IL-6 serum levels remained as a predictor of biochemical recurrence (p=0.040). CONCLUSION: The results presented here demonstrated the usefulness of IL-6 in predicting the biochemical progression of prostate cancer, pointing towards an association between inflammation and the aggressiveness of the tumor. | - |
dc.format.extent | 4 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | International Institute of Anticancer Research | - |
dc.relation.isformatof | Reproducció del document publicat a: http://ar.iiarjournals.org/content/30/10/4369.long | - |
dc.relation.ispartof | Anticancer Research, 2010, vol. 30, num. 10, p. 4369-4372 | - |
dc.rights | (c) International Institute of Anticancer Research, 2010 | - |
dc.source | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) | - |
dc.subject.classification | Càncer de pròstata | - |
dc.subject.classification | Tumors | - |
dc.subject.classification | Marcadors tumorals | - |
dc.subject.other | Prostate cancer | - |
dc.subject.other | Tumors | - |
dc.subject.other | Tumor markers | - |
dc.title | Prognostic value of IL-6 in the localized prostatic cancer | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 621775 | - |
dc.date.updated | 2019-04-10T18:10:16Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 21036766 | - |
Appears in Collections: | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) |
Files in This Item:
File | Description | Size | Format | |
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621775.pdf | 2.73 MB | Adobe PDF | View/Open |
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