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http://hdl.handle.net/2445/133597
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DC Field | Value | Language |
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dc.contributor.author | Esteve-Pastor, María Asunción | - |
dc.contributor.author | García-Fernández, Amaya | - |
dc.contributor.author | Macías, Manuel | - |
dc.contributor.author | Sogorb, Francisco | - |
dc.contributor.author | Valdés, Mariano | - |
dc.contributor.author | Roldán, Vanesa | - |
dc.contributor.author | Muñiz, Javier | - |
dc.contributor.author | Badimón, Lina, 1953- | - |
dc.contributor.author | Roldán, Inmaculada | - |
dc.contributor.author | Bertomeu Martínez, Vicente | - |
dc.contributor.author | Cequier Fillat, Àngel R. | - |
dc.contributor.author | Lip, Gregory Y.H. | - |
dc.contributor.author | Anguita, Manuel | - |
dc.contributor.author | Marín, Francisco | - |
dc.date.accessioned | 2019-05-21T12:37:07Z | - |
dc.date.available | 2019-05-21T12:37:07Z | - |
dc.date.issued | 2016-09-23 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | http://hdl.handle.net/2445/133597 | - |
dc.description.abstract | Background: several bleeding risk scores have been validated in patients with atrial fibrillation (AF). The ORBIT score has been recently proposed as a simple score with the best ability to predict major bleeding. The present study aimed to test the hypothesis that the ORBIT score was superior to the HAS-BLED score for predicting major bleeding and death in "real world" anticoagulated AF patients. Methods and results: we analyzed the predictive performance for bleeding and death of 406 AF patients who underwent 571 electrical cardioversion procedures and 1,276 patients with permanent/persistent AF from the FANTASIIA registry. In the cardioversion population, 21 patients had major bleeding events and 26 patients died. The predictive performance for major bleeding of HAS-BLED and ORBIT were not significantly different (c-statistics 0.77 (95% CI 0.66-0.88) and 0.82 (95% CI 0.77-0.93), respectively; P=0.080). For the FANTASIIA population, 46 patients had major bleeding events and 50 patients died. The predictive performances for major bleeding of HASBLED and ORBIT were not significantly different (c-statistics 0.63 (95% CI 0.56-0.71) and 0.70 (95% CI 0.62-0.77), respectively; P=0.116). For death, the predictive performances of HAS-BLED and ORBIT were not significantly different in both populations. The ORBIT score categorized most patients as "low risk". Conclusions: despite the original claims in its derivation paper, the ORBIT score was not superior to HAS-BLED for predicting major bleeding and death in a "real world" oral anticoagulated AF population. (Circ J 2016; 80:2102 - 2108) | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Japanese Circulation Society | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1253/circj.CJ-16-0471 | - |
dc.relation.ispartof | Circulation Journal, 2016, vol. 80, num. 10, p. 2102-2108 | - |
dc.relation.uri | https://doi.org/10.1253/circj.CJ-16-0471 | - |
dc.rights | (c) Japanese Circulation Society, 2016 | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Fibril·lació auricular | - |
dc.subject.classification | Paravents | - |
dc.subject.classification | Efectes secundaris dels medicaments | - |
dc.subject.classification | Hemorràgia | - |
dc.subject.classification | Coagulació | - |
dc.subject.other | Atrial fibrillation | - |
dc.subject.other | Screens | - |
dc.subject.other | Drug side effects | - |
dc.subject.other | Hemorrhage | - |
dc.subject.other | Coagulation | - |
dc.title | Is the ORBIT bleeding risk score superior to the HAS-BLED score in anticoagulated atrial fibrillation patients? | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 664704 | - |
dc.date.updated | 2019-05-21T12:37:07Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 27557850 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) |
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File | Description | Size | Format | |
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664704.pdf | 321.58 kB | Adobe PDF | View/Open |
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