Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/134787
Title: | Condensation Transition in DNA-Polyaminoamide Dendrimer Fibers Studied Using Optical Tweezers |
Author: | Ritort Farran, Fèlix Mihardja, S. Smith, S.B. Bustamante, C.J. |
Keywords: | Condensació Experiments Condensation Experiments |
Issue Date: | 22-Mar-2006 |
Publisher: | American Physical Society |
Abstract: | When mixed together, DNA and polyaminoamide dendrimers form fibers that condense into a compact structure. We use optical tweezers to pull condensed fibers and investigate the decondensation transition by measuring force-extension curves (FECs). A characteristic force plateau (around 10 pN) and hysteresis between the pulling and relaxation cycles are observed for different dendrimer sizes, indicating the existence of a first-order transition between two phases (condensed and extended) of the fiber. Upon salt variation FECs change noticeably confirming that electrostatic forces drive the condensation transition. We propose a simple model for the decondensing transition that qualitatively reproduces the FECs and which is confirmed by atomic force microscopy images. |
Note: | Reproducció del document publicat a: https://doi.org/10.1103/PhysRevLett.96.118301 |
It is part of: | Physical Review Letters, 2006, vol. 96, num. 11, p. 118301 |
URI: | http://hdl.handle.net/2445/134787 |
Related resource: | https://doi.org/10.1103/PhysRevLett.96.118301 |
ISSN: | 0031-9007 |
Appears in Collections: | Articles publicats en revistes (Física de la Matèria Condensada) |
Files in This Item:
File | Description | Size | Format | |
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602514.pdf | 863.85 kB | Adobe PDF | View/Open |
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