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http://hdl.handle.net/2445/145578
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DC Field | Value | Language |
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dc.contributor.author | Roca Millan, Elisabet | - |
dc.contributor.author | González Navarro, Beatriz | - |
dc.contributor.author | Sabater Recolons, Ma. del Mar | - |
dc.contributor.author | Marí Roig, Antonio | - |
dc.contributor.author | Jané Salas, Enric | - |
dc.contributor.author | López López, José, 1958- | - |
dc.date.accessioned | 2019-11-27T19:21:46Z | - |
dc.date.available | 2019-11-27T19:21:46Z | - |
dc.date.issued | 2018-11-01 | - |
dc.identifier.issn | 1698-4447 | - |
dc.identifier.uri | http://hdl.handle.net/2445/145578 | - |
dc.description | Podeu consultar la versió en castellà del document a: http://hdl.handle.net/2445/153580 | - |
dc.description.abstract | Background: atherosclerotic cardiovascular disease is the main cause of mortality in developed countries. It is a chronic and systemic inflammatory disease with a multifactorial etiology. Periodontal disease is one of the many factors that contribute to its development. Objective: to analyze the effects of periodontal treatment on cardiovascular risk parameters in patients with atherosclerotic cardiovascular disease. Methods: a systematic research was conducted in the Pubmed/Medline databases for clinical trials published up to and including the year 2017. Results: ten articles were included for analysis. Periodontal treatment reduced C-reactive protein levels (77.8% of clinical trials), tumor necrosis factor-alpha (66.7%), interleukin-6 (100%) and leukocytes (50%). Fibrinogen levels also improved considerably (66.7%). Effects on lipid parameters were more limited, whereby only oxidized low density lipoprotein and very low density lipoprotein cholesterol decreased significantly. Meta-analysis showed a statistically significant decreased in C-reactive protein and leukocytes values when patients were submitted to non-surgical periodontal treatment in contrast to receiving no treatment at all (mean difference 1.199 mg/L, 95% confidence interval: 1.100-1.299, p<0.001; and mean difference 0,79 g/L, 95% confidence interval: 0.717-0.879, p<0.001, respectively). Conclusions: periodontal treatment has a beneficial effect on some of the biochemical parameters considered to represent cardiovascular risk. Further randomized clinical trials are necessary, with longer follow-up periods including regular periodic monitoring, in order to determine the extent of the impact of periodontal treatment. | - |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Medicina Oral SL | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.4317/medoral.22725 | - |
dc.relation.ispartof | Medicina Oral, Patología Oral y Cirugía Bucal, 2018, vol. 23, num. 6, p. 681-690 | - |
dc.relation.uri | https://doi.org/10.4317/medoral.22725 | - |
dc.rights | (c) Medicina Oral SL, 2018 | - |
dc.source | Articles publicats en revistes (Odontoestomatologia) | - |
dc.subject.classification | Malalties periodontals | - |
dc.subject.classification | Malalties cardiovasculars | - |
dc.subject.classification | Aterosclerosi | - |
dc.subject.other | Periodontal disease | - |
dc.subject.other | Cardiovascular diseases | - |
dc.subject.other | Atherosclerosis | - |
dc.title | Periodontal treatment on patients with cardiovascular disease: systematic review and meta-analysis | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 683652 | - |
dc.date.updated | 2019-11-27T19:21:46Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 30341272 | - |
Appears in Collections: | Articles publicats en revistes (Odontoestomatologia) Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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683652.pdf | 1.16 MB | Adobe PDF | View/Open |
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