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http://hdl.handle.net/2445/151828
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DC Field | Value | Language |
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dc.contributor.author | López Pelayo, Hugo | - |
dc.contributor.author | Miquel de Montagut, Laia | - |
dc.contributor.author | Altamirano, José | - |
dc.contributor.author | Bataller Alberola, Ramón | - |
dc.contributor.author | Caballeria Rovira, Joan | - |
dc.contributor.author | Ortega, Lluisa | - |
dc.contributor.author | Lligoña, Anna | - |
dc.contributor.author | Gual, Antoni | - |
dc.date.accessioned | 2020-03-03T15:35:09Z | - |
dc.date.available | 2020-03-03T15:35:09Z | - |
dc.date.issued | 2019-01-01 | - |
dc.identifier.issn | 0022-3999 | - |
dc.identifier.uri | http://hdl.handle.net/2445/151828 | - |
dc.description.abstract | Aims: Alcoholic hepatitis (AH) is a life-threatening complication of alcohol use disorder (AUD). Alcohol abstinence is the main predictor of the long-term prognosis of AH. It is unknown whether AUD treatment retention (TR) after an AH episode impacts alcohol relapse and mortality or what baseline factors influence TR. Methods: Design: case-control study; Study population: hospitalized patients (1999-2012) with an episode of biopsy-proven AH were included (n = 120); Assessment: demographic and clinical data, the High-Risk Alcoholism Relapse (HRAR) scale, mortality and alcohol relapse were assessed through clinical records and telephone or personal interviews; Follow-up period: short-term and long-term TRs were assessed at 12 and 24 months, respectively. Results: The overall short-term and long-term TRs were 37% and 27.8%, respectively. The severity of liver disease at baseline predicted both short-term and long-term TR (OR 3.7 and 3.3, respectively), whereas HRAR >3 and a history of psychiatric disorders predicted long-term TR (OR 2.9 and 2.6, respectively). Moreover, HRAR >3 (OR 3.0) and previous treatment for AUD (OR 2.9) increased the risk of relapse in the short term. Importantly, receiving alcohol therapy in a centre different from the hospital where the patient was admitted was associated with increased risk of alcohol relapse over the long term (OR 5.4). Conclusion: Experiencing an alcohol-related life-threatening complication is insufficient motivation to seek treatment for AUD. AUD treatment after an episode of AH is suboptimal, with a low TR rate, high risk of alcohol relapse and poor impact of treatment on alcohol relapse. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier B.V. | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1016/j.jpsychores.2018.11.020 | - |
dc.relation.ispartof | Journal of Psychosomatic Research, 2019, vol. 116, p. 75-82 | - |
dc.relation.uri | https://doi.org/10.1016/j.jpsychores.2018.11.020 | - |
dc.rights | cc-by-nc-nd (c) Elsevier B.V., 2019 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Hepatitis | - |
dc.subject.classification | Consum d'alcohol | - |
dc.subject.other | Hepatitis | - |
dc.subject.other | Drinking of alcoholic beverages | - |
dc.title | Treatment retention in a specialized alcohol programme after an episode of alcoholic hepatitis: Impact on alcohol relapse | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 689864 | - |
dc.date.updated | 2020-03-03T15:35:09Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 30654998 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) |
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