Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/151828
Title: | Treatment retention in a specialized alcohol programme after an episode of alcoholic hepatitis: Impact on alcohol relapse |
Author: | López Pelayo, Hugo Miquel de Montagut, Laia Altamirano, José Bataller Alberola, Ramón Caballeria Rovira, Joan Ortega, Lluisa Lligoña, Anna Gual, Antoni |
Keywords: | Hepatitis Consum d'alcohol Hepatitis Drinking of alcoholic beverages |
Issue Date: | 1-Jan-2019 |
Publisher: | Elsevier B.V. |
Abstract: | Aims: Alcoholic hepatitis (AH) is a life-threatening complication of alcohol use disorder (AUD). Alcohol abstinence is the main predictor of the long-term prognosis of AH. It is unknown whether AUD treatment retention (TR) after an AH episode impacts alcohol relapse and mortality or what baseline factors influence TR. Methods: Design: case-control study; Study population: hospitalized patients (1999-2012) with an episode of biopsy-proven AH were included (n = 120); Assessment: demographic and clinical data, the High-Risk Alcoholism Relapse (HRAR) scale, mortality and alcohol relapse were assessed through clinical records and telephone or personal interviews; Follow-up period: short-term and long-term TRs were assessed at 12 and 24 months, respectively. Results: The overall short-term and long-term TRs were 37% and 27.8%, respectively. The severity of liver disease at baseline predicted both short-term and long-term TR (OR 3.7 and 3.3, respectively), whereas HRAR >3 and a history of psychiatric disorders predicted long-term TR (OR 2.9 and 2.6, respectively). Moreover, HRAR >3 (OR 3.0) and previous treatment for AUD (OR 2.9) increased the risk of relapse in the short term. Importantly, receiving alcohol therapy in a centre different from the hospital where the patient was admitted was associated with increased risk of alcohol relapse over the long term (OR 5.4). Conclusion: Experiencing an alcohol-related life-threatening complication is insufficient motivation to seek treatment for AUD. AUD treatment after an episode of AH is suboptimal, with a low TR rate, high risk of alcohol relapse and poor impact of treatment on alcohol relapse. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1016/j.jpsychores.2018.11.020 |
It is part of: | Journal of Psychosomatic Research, 2019, vol. 116, p. 75-82 |
URI: | http://hdl.handle.net/2445/151828 |
Related resource: | https://doi.org/10.1016/j.jpsychores.2018.11.020 |
ISSN: | 0022-3999 |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
689864.pdf | 835.75 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License