Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/163721
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DC Field | Value | Language |
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dc.contributor.author | Paulo de Andrade, Jean | - |
dc.contributor.author | Giordani, R. B. | - |
dc.contributor.author | Torras Claveria, Laura | - |
dc.contributor.author | Pigni, Natalia Belén | - |
dc.contributor.author | Berkov, Strahil | - |
dc.contributor.author | Font Bardia, Ma. Mercedes | - |
dc.contributor.author | Calvet Pallàs, Maria Teresa | - |
dc.contributor.author | Konrath, E. | - |
dc.contributor.author | Bueno, K. | - |
dc.contributor.author | Sachett, L. G. | - |
dc.contributor.author | Dutilh, J. H. | - |
dc.contributor.author | Borges, W. D. | - |
dc.contributor.author | Viladomat Meya, Francesc | - |
dc.contributor.author | Henriques, A. T. | - |
dc.contributor.author | Nair, Jerald J. | - |
dc.contributor.author | Zuanazzi, José Ângelo Silveira | - |
dc.contributor.author | Bastida Armengol, Jaume | - |
dc.date.accessioned | 2020-06-02T11:13:06Z | - |
dc.date.available | 2020-06-02T11:13:06Z | - |
dc.date.issued | 2016-02 | - |
dc.identifier.issn | 1568-7767 | - |
dc.identifier.uri | http://hdl.handle.net/2445/163721 | - |
dc.description.abstract | Nine Brazilian Amaryllidaceae species were studied for their alkaloid composition and acetylcholinesterase (AChE) inhibitory activity via GC-MS and a modified Ellman assay, respectively. A total of thirty-six alkaloids were identified in these plants, of which Hippeastrum papilio and H. glau-cescens exhibited the highest galanthamine content and the best IC50 values against AChE. Furthermore, Hippeastrum vittatum and Rhodophiala bifida also showed notable AChE inhibitory effects. X-ray crys-tallographic data for four galanthamine-type com-pounds revealed significant differences in the orientation of theN-methyl group, which are shown to be related to AChE inhibition. | - |
dc.format.extent | 24 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Springer Science + Business Media | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1007/s11101-015-9411-7 | - |
dc.relation.ispartof | Phytochemistry Reviews, 2016, vol. 15, num. 1, p. 147-160 | - |
dc.relation.uri | https://doi.org/10.1007/s11101-015-9411-7 | - |
dc.rights | (c) Springer Science + Business Media, 2016 | - |
dc.source | Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada) | - |
dc.subject.classification | Alcaloides | - |
dc.subject.classification | Radiocristal·lografia | - |
dc.subject.other | Alkaloids | - |
dc.subject.other | X-ray crystallography | - |
dc.title | The brazilian Amaryllidaceae as a source of acetylcholinesterase inhibitory alkaloids | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 656974 | - |
dc.date.updated | 2020-06-02T11:13:06Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada) |
Files in This Item:
File | Description | Size | Format | |
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656974.pdf | 1.13 MB | Adobe PDF | View/Open |
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