Please use this identifier to cite or link to this item:
Title: A cross-sectional and longitudinal study on the protective effect of bilingualism against dementia using brain atrophy and cognitive measures
Author: Costumero, Víctor
Marin Marin, Lidon
Calabria, Marco
Belloch, Vicente
Escudero, Joaquín
Baquero, Miguel
Hernández Pardo, Mireia
Ruiz de Miras, Juan
Costa, Albert, 1970-
Parcet, Maria Antònia
Ávila, César
Keywords: Bilingüisme
Malaltia d'Alzheimer
Alzheimer's disease
Issue Date: 2020
Publisher: BioMed Central
Abstract: Background: Evidence from previous studies suggests that bilingualism contributes to cognitive reserve because bilinguals manifest the first symptoms of Alzheimer's disease (AD) up to 5 years later than monolinguals. Other cross-sectional studies demonstrate that bilinguals show greater amounts of brain atrophy and hypometabolism than monolinguals, despite sharing the same diagnosis and suffering from the same symptoms. However, these studies may be biased by possible pre-existing between-group differences. Methods: In this study, we used global parenchymal measures of atrophy and cognitive tests to investigate the protective effect of bilingualism against dementia cross-sectionally and prospectively, using a sample of bilinguals and monolinguals in the same clinical stage and matched on sociodemographic variables. Results: Our results suggest that the two groups did not differ in their cognitive status at baseline, but bilinguals had less parenchymal volume than monolinguals, especially in areas related to brain atrophy in dementia. In addition, a longitudinal prospective analysis revealed that monolinguals lost more parenchyma and had more cognitive decline than bilinguals in a mean follow-up period of 7 months. Conclusion: These results provide the first prospective evidence that bilingualism may act as a neuroprotective factor against dementia and could be considered a factor in cognitive reserve.
Note: Reproducció del document publicat a:
It is part of: Alzheimers Research & Therapy, 2020, vol. 12, p. 11
Related resource:
ISSN: 1758-9193
Appears in Collections:Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Files in This Item:
File Description SizeFormat 
700446.pdf873.34 kBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons