Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/164139
Title: | A practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines |
Author: | Amat Tusón, Mercedes Navío, Laura Llor Brunés, Núria Molins, Elies Bosch Cartes, Joan |
Keywords: | Síntesi orgànica Lactames Enantiòmers Compostos heterocíclics Organic synthesis Lactams Enantiomers Heterocyclic compounds |
Issue Date: | 6-Jan-2012 |
Publisher: | American Chemical Society |
Abstract: | Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of an unsaturated δ-keto ester derivative with (R)-phenylglycinol and the stereoselective hydrogenation of the resulting tricyclic oxazoloquinolone lactams. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1021/ol2030058 |
It is part of: | Organic Letters, 2012, vol. 14, num. 1, p. 210-213 |
URI: | http://hdl.handle.net/2445/164139 |
Related resource: | https://doi.org/10.1021/ol2030058 |
ISSN: | 1523-7060 |
Appears in Collections: | Articles publicats en revistes (Institut de Biomedicina (IBUB)) Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
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