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http://hdl.handle.net/2445/164139| Title: | A practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines |
| Author: | Amat Tusón, Mercedes Navío, Laura Llor Brunés, Núria Molins, Elies Bosch Cartes, Joan |
| Keywords: | Síntesi orgànica Lactames Enantiòmers Compostos heterocíclics Organic synthesis Lactams Enantiomers Heterocyclic compounds |
| Issue Date: | 6-Jan-2012 |
| Publisher: | American Chemical Society |
| Abstract: | Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of an unsaturated δ-keto ester derivative with (R)-phenylglycinol and the stereoselective hydrogenation of the resulting tricyclic oxazoloquinolone lactams. |
| Note: | Versió postprint del document publicat a: https://doi.org/10.1021/ol2030058 |
| It is part of: | Organic Letters, 2012, vol. 14, num. 1, p. 210-213 |
| URI: | http://hdl.handle.net/2445/164139 |
| Related resource: | https://doi.org/10.1021/ol2030058 |
| ISSN: | 1523-7060 |
| Appears in Collections: | Articles publicats en revistes (Institut de Biomedicina (IBUB)) Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 603300.pdf | 150.84 kB | Adobe PDF | View/Open |
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