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Title: Amphioxus makes the cut Again
Author: Somorjai, Ildikó M. L.
Escrivà, Hector
Garcia Fernández, Jordi
Keywords: Genètica del desenvolupament
Genètica evolutiva
Developmental genetics
Evolutionary genetics
Issue Date: 2012
Publisher: Landes Bioscience
Abstract: The cephalochordate amphioxus is now established as an important model system for understanding the evolution of vertebrate novelties from an invertebrate chordate ancestor. It is also emerging as a serious candidate for studies of organ regeneration. We extend here our previous observations on the European amphioxus´ extensive adult regenerative capacity. The expression of Wnt5 and the presence of β-catenin protein in the early bud-stage blastema support a role for Wnt signaling during tail regeneration in amphioxus. We also present data showing that Branchiostoma lanceolatum continues to regenerate well after repeated amputation of the post-anal tail. These results are discussed in relation to vertebrate regeneration and other stem cell systems, and in the context of regeneration decline with aging.
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It is part of: Communicative & Integrative Biology, 2012, vol. 5, num. 5, p. 499-502
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ISSN: 1942-0889
Appears in Collections:Articles publicats en revistes (Genètica, Microbiologia i Estadística)

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