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https://hdl.handle.net/2445/167518| Title: | Enantioselective Synthesis of Spiro[indolizidine-1,3 '-oxindoles] |
| Author: | Pérez Bosch, Maria Ramos, Carlos Massi, Lucia Gazzola, Silvia Taglienti, Chiara Yayik, Nihan Molins i Grau, Elies Viayna Gaza, Antonio Luque Garriga, F. Xavier Bosch Cartes, Joan Amat Tusón, Mercedes |
| Keywords: | Síntesi orgànica Enantiòmers Oxidació Compostos heterocíclics Organic synthesis Enantiomers Oxidation Heterocyclic compounds |
| Issue Date: | 4-Aug-2017 |
| Publisher: | American Chemical Society |
| Abstract: | A three-step procedure for the enantioselective synthesis of spiro[indolizidine-1,3'-oxindoles], consisting of a stereoselective cyclocondensation reaction between (S)-tryptophanol and a prochiral or racemic 5-oxoester, bromination of the resulting oxazolopiperidone lactam, and a final stereoselective spirocyclization, is reported. |
| Note: | Versió postprint del document publicat a: https://doi.org/10.1021/acs.orglett.71301818 |
| It is part of: | Organic Letters, 2017, vol. 19, num. 15, p. 4050-4053 |
| URI: | https://hdl.handle.net/2445/167518 |
| Related resource: | https://doi.org/10.1021/acs.orglett.71301818 |
| ISSN: | 1523-7060 |
| Appears in Collections: | Articles publicats en revistes (Institut de Biomedicina (IBUB)) Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) |
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|---|---|---|---|---|
| 677697.pdf | 708.14 kB | Adobe PDF | View/Open |
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