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Title: Enantioselective Synthesis of Spiro[indolizidine-1,3 '-oxindoles]
Author: Pérez Bosch, Maria
Ramos, Carlos
Massi, Lucia
Gazzola, Silvia
Taglienti, Chiara
Yayik, Nihan
Molins i Grau, Elies
Viayna Gaza, Antonio
Luque Garriga, F. Xavier
Bosch Cartes, Joan
Amat Tusón, Mercedes
Keywords: Síntesi orgànica
Compostos heterocíclics
Organic synthesis
Heterocyclic compounds
Issue Date: 4-Aug-2017
Publisher: American Chemical Society
Abstract: A three-step procedure for the enantioselective synthesis of spiro[indolizidine-1,3'-oxindoles], consisting of a stereoselective cyclocondensation reaction between (S)-tryptophanol and a prochiral or racemic 5-oxoester, bromination of the resulting oxazolopiperidone lactam, and a final stereoselective spirocyclization, is reported.
Note: Versió postprint del document publicat a:
It is part of: Organic Letters, 2017, vol. 19, num. 15, p. 4050-4053
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ISSN: 1523-7060
Appears in Collections:Articles publicats en revistes (Institut de Biomedicina (IBUB))
Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)

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