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Title: | Interlaboratory Coverage Test on Plant Food Bioactive Compounds and their Metabolites by Mass Spectrometry-Based Untargeted Metabolomics. |
Author: | Koistinen, Ville Mikael Bento da Silva, Andreia Abrankó, László Low, Dorrain Yanwen Garcia Villalba, Rocio Tomas-Barberan, F. A. (Francisco A.) Landberg, Rikard Savolainen, Otto Alvarez-Acero, Inmaculada Pascual-Teresa, Sonia de Van Poucke, Christof Almeida, Conceição Petrásková, Lucie Valentová, Kateřina Durand, Stephanie Wiczkowski, Wiesław Szawara-Nowak, Dorota González-Domínguez, Raúl Llorach, Rafael Andrés Lacueva, Ma. Cristina Aura, Anna-Marja Seppänen-Laakso, Tuulikki Hanhineva, Kati Manach, Claudine Bronze, Maria Rosario |
Keywords: | Espectrometria de masses Fitoquímica Metabolòmica Plantes comestibles Compostos bioactius vegetals Dieta Mass spectrometry Botanical chemistry Metabolomics Edible plants Plant bioactive compounds Diet |
Issue Date: | 24-Aug-2018 |
Publisher: | MDPI |
Abstract: | Bioactive compounds present in plant-based foods, and their metabolites derived from gut microbiota and endogenous metabolism, represent thousands of chemical structures of potential interest for human nutrition and health. State-of-the-art analytical methodologies, including untargeted metabolomics based on high-resolution mass spectrometry, are required for the profiling of these compounds in complex matrices, including plant food materials and biofluids. The aim of this project was to compare the analytical coverage of untargeted metabolomics methods independently developed and employed in various European platforms. In total, 56 chemical standards representing the most common classes of bioactive compounds spread over a wide chemical space were selected and analyzed by the participating platforms (n = 13) using their preferred untargeted method. The results were used to define analytical criteria for a successful analysis of plant food bioactives. Furthermore, they will serve as a basis for an optimized consensus method. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/metabo8030046 |
It is part of: | Metabolites, 2018, vol. 8, num. 3, p. 46 |
URI: | http://hdl.handle.net/2445/168071 |
Related resource: | https://doi.org/10.3390/metabo8030046 |
ISSN: | 2218-1989 |
Appears in Collections: | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) |
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