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http://hdl.handle.net/2445/171703
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DC Field | Value | Language |
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dc.contributor.author | Hernáez Camba, Álvaro | - |
dc.contributor.author | Castañer, Olga | - |
dc.contributor.author | Tresserra i Rimbau, Anna | - |
dc.contributor.author | Pintó Sala, Xavier | - |
dc.contributor.author | Fitó Colomer, Montserrat | - |
dc.contributor.author | Casas Rodríguez, Rosa M. | - |
dc.contributor.author | Martínez-González, Miguel Ángel, 1957- | - |
dc.contributor.author | Corella Piquer, Dolores | - |
dc.contributor.author | Salas Salvadó, Jordi | - |
dc.contributor.author | Lapetra, José | - |
dc.contributor.author | Gómez-Gracia, Enrique | - |
dc.contributor.author | Arós, Fernando | - |
dc.contributor.author | Fiol Sala, Miguel | - |
dc.contributor.author | Serra Majem, Lluís | - |
dc.contributor.author | Ros Rahola, Emilio | - |
dc.contributor.author | Estruch Riba, Ramon | - |
dc.date.accessioned | 2020-11-03T06:41:03Z | - |
dc.date.available | 2021-12-31T06:10:20Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 1613-4125 | - |
dc.identifier.uri | http://hdl.handle.net/2445/171703 | - |
dc.description.abstract | Scope: To assess whether following a Mediterranean diet (MedDiet) improves atherothrombosis biomarkers in high cardiovascular risk individuals. Methods and results: In 358 random volunteers from the PREvención con DIeta MEDiterránea trial, the 1-year effects on atherothrombosis markers of an intervention with MedDiet, enriched with virgin olive oil (MedDiet-VOO; n = 120) or nuts (MedDiet-Nuts; n = 119) versus a low-fat control diet (n = 119), and whether large increments in MedDiet adherence (≥3 score points, versus compliance decreases) and intake changes in key food items are associated with 1-year differences in biomarkers. Differences are observed between 1-year changes in the MedDiet-VOO intervention and control diet on the activity of platelet activating factor acetylhydrolase in high-density lipoproteins (HDLs) (+7.5% [95% confidence interval: 0.17; 14.8]) and HDL-bound 𝜶1-antitrypsin levels (−6.1% [−11.8; −0.29]), and between the MedDiet-Nuts intervention and the control arm on non-esterified fatty acid concentrations (−9.3% [−18.1; −0.53]). Large MedDiet adherence increments are associated with less fibrinogen (−9.5% [−18.3; −0.60]) and non-esterified fatty acid concentrations (−16.7% [−31.7; −1.74]). Increases in nut, fruit, vegetable, and fatty fish consumption, and decreases in processed meat intake are linked to enhancements in biomarkers. Conclusion: MedDiet improves atherothrombosis biomarkers in high cardiovascular risk individuals. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Wiley-VCH | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1002/mnfr.202000350 | - |
dc.relation.ispartof | Molecular Nutrition & Food Research, 2020 | - |
dc.relation.uri | https://doi.org/10.1002/mnfr.202000350 | - |
dc.rights | (c) Wiley-VCH, 2020 | - |
dc.source | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) | - |
dc.subject.classification | Cuina mediterrània | - |
dc.subject.classification | Dieta | - |
dc.subject.classification | Malalties cardiovasculars | - |
dc.subject.other | Mediterranean cooking | - |
dc.subject.other | Diet | - |
dc.subject.other | Cardiovascular diseases | - |
dc.title | Mediterranean Diet and Atherothrombosis Biomarkers: A Randomized Controlled Trial | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 704074 | - |
dc.date.updated | 2020-11-03T06:41:04Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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704074.pdf | 618.26 kB | Adobe PDF | View/Open |
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