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http://hdl.handle.net/2445/173621
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DC Field | Value | Language |
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dc.contributor.author | Sánchez Garcés, Ma. Ángeles | - |
dc.contributor.author | Camps Font, Octavi | - |
dc.contributor.author | Escoda Francolí, Jaume | - |
dc.contributor.author | Muñoz Guzón, Fernando | - |
dc.contributor.author | Toledano Serrabona, Jorge | - |
dc.contributor.author | Gay Escoda, Cosme | - |
dc.date.accessioned | 2021-02-03T12:13:07Z | - |
dc.date.available | 2021-02-03T12:13:07Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 1698-4447 | - |
dc.identifier.uri | http://hdl.handle.net/2445/173621 | - |
dc.description.abstract | Background: The aim of this histomorphometric study was to assess the bone regeneration potential of beta-tricalcium phosphate with fibronectin (β-TCP-Fn) in critical-sized defects (CSDs) in rats calvarial, to know whether Fn improves the new bone formation in a short time scope. Material and Methods: CSDs were created in 30 Sprague Dawley rats, and divided into four groups (2 or 6 weeks of healing) and type of filling (β-TCP-Fn, β-TCP, empty control). Variables studied were augmented area (AA), gained tissue (GT), mineralized/non mineralized bone matrix (MBM/NMT) and bone substitute (BS). Results: 60 samples at 2 and six weeks were evaluated. AA was higher for treatment groups comparing to controls (p < 0.001) and significant decrease in BS area in the β-TCP-Fn group from 2 to 6 weeks (p = 0.031). GT was higher in the β-TCP-Fn group than in the controls expressed in % (p = 0.028) and in mm2 (p = 0.011), specially at two weeks (p=0.056). Conclusions: Both β-TCP biomaterials are effective as compared with bone defects left empty in maintaining the volume. GT in defects regeneration filed with β-TCP-Fn are significantly better in short healing time when comparing with controls but not for β-TCP used alone in rats calvarial CSDs. | - |
dc.format.extent | 9 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Medicina Oral SL | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.4317/medoral.23564 | - |
dc.relation.ispartof | Medicina Oral, Patología Oral y Cirugía Bucal, 2020, vol. 25, num. 4, p. e532-e540 | - |
dc.relation.uri | https://doi.org/10.4317/medoral.23564 | - |
dc.rights | (c) Medicina Oral SL, 2020 | - |
dc.source | Articles publicats en revistes (Odontoestomatologia) | - |
dc.subject.classification | Regeneració (Biologia) | - |
dc.subject.classification | Malalties dels ossos | - |
dc.subject.classification | Rates (Animals de laboratori) | - |
dc.subject.other | Regeneration (Biology) | - |
dc.subject.other | Bone diseases | - |
dc.subject.other | Rats as laboratory animals | - |
dc.title | Short time guided bone regeneration using beta-tricalcium phosphate with and without fibronectin. An experimental study in rats | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 702062 | - |
dc.date.updated | 2021-02-03T12:13:08Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 32388521 | - |
Appears in Collections: | Articles publicats en revistes (Odontoestomatologia) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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702062.pdf | 1.67 MB | Adobe PDF | View/Open |
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