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Title: | A Straightforward Synthesis of Functionalized cis-Perhydroisoquinolin-1-ones |
Author: | Arioli, Federica Pérez Bosch, Maria Are, Celeste Molins i Grau, Elies Bosch Cartes, Joan Amat Tusón, Mercedes |
Keywords: | Indicadors (Química) Proves i reactius químics Lactames Química orgànica Indicators and test-papers Chemical tests and reagents Lactams Organic chemistry |
Issue Date: | Jan-2019 |
Publisher: | MDPI |
Abstract: | Base-catalyzed annulation reactions of 5,6-dihydro-2(1H)-pyridones with Nazarov-type reagents are reported. The effect of the solvent polarity and the concentration of the reagents is studied. The process involves two successive Michael additions and stereoselectively provides functionalized cis-perhydroisoquinolin-1-ones. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/molecules24030557 |
It is part of: | Molecules, 2019, vol. 24, p. 557-570 |
URI: | http://hdl.handle.net/2445/174410 |
Related resource: | https://doi.org/10.3390/molecules24030557 |
ISSN: | 1420-3049 |
Appears in Collections: | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
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