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http://hdl.handle.net/2445/174616
Title: | Gut Health-Promoting Benefits of a Dietary Supplement of Vitamins with Inulin and Acacia Fibers in Rats |
Author: | Massot Cladera, Malen Azagra Boronat, Ignasi Franch i Masferrer, Àngels Castell, Margarida Rodríguez Lagunas, María José Pérez-Cano, Francisco J. |
Keywords: | Intestins Microbiota intestinal Suplements nutritius Rates (Animals de laboratori) Intestines Gastrointestinal microbiome Dietary supplements Rats as laboratory animals |
Issue Date: | 23-Jul-2020 |
Publisher: | MDPI |
Abstract: | The study's objective was to ascertain whether a nutritional multivitamin and mineral supplement enriched with two different dietary fibers influences microbiota composition, mineral absorption, and some immune and metabolic biomarkers in adult rats. Nine-week-old Wistar rats were randomly assigned into four groups: the reference group; the group receiving a daily supplement based on a food matrix with proteins, vitamins, and minerals; and two other groups receiving this supplement enriched with inulin (V + I) or acacia (V + A) fiber for four weeks. Microbiota composition was determined in cecal content and mineral content in fecal, blood, and femur samples. Intestinal IgA concentration, hematological, and biochemical variables were evaluated. Both V + I and V + A supplementations increased Firmicutes and Actinobacteria phyla, which were associated with a higher presence of Lactobacillus and Bifidobacterium spp. V + A supplementation increased calcium, magnesium, phosphorus, and zinc concentrations in femur. V + I supplementation increased the fecal IgA content and reduced plasma total cholesterol and uric acid concentration. Both fiber-enriched supplements tested herein seem to be beneficial to gut-health, although differently. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/nu12082196 |
It is part of: | Nutrients, 2020, vol. 12(8) |
URI: | http://hdl.handle.net/2445/174616 |
Related resource: | https://doi.org/10.3390/nu12082196 |
ISSN: | 2072-6643 |
Appears in Collections: | Articles publicats en revistes (Bioquímica i Fisiologia) |
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