1. Dipòsit Digital de la Universitat de Barcelona
  2. Recerca
  3. Ciències Fisiològiques
  4. Articles publicats en revistes (Ciències Fisiològiques)
Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/176325
Full metadata record
DC FieldValueLanguage
dc.contributor.authorEsteller, Manel-
dc.date.accessioned2021-04-15T10:35:56Z-
dc.date.available2021-04-15T10:35:56Z-
dc.date.issued2008-03-13-
dc.identifier.issn0028-4793-
dc.identifier.urihttp://hdl.handle.net/2445/176325-
dc.description.abstractClassic genetics alone cannot explain the diversity of phenotypes within a population. Nor does classic genetics explain how, despite their identical DNA sequences, monozygotic twins or cloned animals can have different phenotypes and different susceptibilities to a disease. The concept of epigenetics offers a partial explanation of these phenomena. First introduced by C.H. Waddington in 1939 to name "the causal interactions between genes and their products, which bring the phenotype into being," epigenetics was later defined as heritable changes in gene expression that are not due to any alteration in the DNA sequence.-
dc.format.extent12 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherMassachusetts Medical Society-
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1056/NEJMra072067-
dc.relation.ispartofNew England Journal of Medicine, 2008, vol. 358, num. 11, p. 1148-1159-
dc.relation.urihttps://doi.org/10.1056/NEJMra072067-
dc.rights(c) Massachusetts Medical Society, 2008-
dc.sourceArticles publicats en revistes (Ciències Fisiològiques)-
dc.subject.classificationADN-
dc.subject.classificationEpigènesi-
dc.subject.classificationExpressió gènica-
dc.subject.classificationProteïnes supressores de tumors-
dc.subject.classificationFisiologia-
dc.subject.otherDNA-
dc.subject.otherEpigenesis-
dc.subject.otherGene expression-
dc.subject.otherTumor suppressor protein-
dc.subject.otherPhysiology-
dc.titleEpigenetics in Cancer-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.identifier.idgrec699623-
dc.date.updated2021-04-15T10:35:57Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid18337604-
Appears in Collections:Articles publicats en revistes (Ciències Fisiològiques)

Files in This Item:
File Description SizeFormat 
699623.pdf472.47 kBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.