Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/176579
Title: | Time-to-Treatment in Oral Cancer: Causes and Implications for Survival |
Author: | Saka Herrán, Constanza Jané Salas, Enric Marí Roig, Antonio Estrugo Devesa, Albert López López, José, 1958- |
Keywords: | Càncer de boca Càncer de coll Càncer de cap Diagnòstic Oral cancer Neck cancer Head cancer Diagnosis |
Issue Date: | 16-Mar-2021 |
Publisher: | MDPI |
Abstract: | The purpose of this review was to identify and describe the causes that influence the time-intervals in the pathway of diagnosis and treatment of oral cancer and to assess its impact on prognosis and survival. The review was structured according to the recommendations of the Aarhus statement, considering original data from individual studies and systematic reviews that reported outcomes related to the patient, diagnostic and pre-treatment intervals. The patient interval is the major contributor to the total time-interval. Unawareness of signs and/or symptoms, denial and lack of knowledge about oral cancer are the major contributors to the process of seeking medical attention. The diagnostic interval is influenced by tumor factors, delays in referral due to higher number of consultations and previous treatment with different medicines or dental procedures and by professional factors such as experience and lack of knowledge related to the disease and diagnostic procedures. Patients with advanced stage disease, primary treatment with radiotherapy, treatment at an academic facility and transitions in care are associated with prolonged pre-treatment intervals. An emerging body of evidence supports the impact of prolonged pre-treatment and treatment intervals with poorer survival from oral cancer. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/cancers13061321 |
It is part of: | Cancers, 2021, vol 13, num. 6 |
URI: | http://hdl.handle.net/2445/176579 |
Related resource: | https://doi.org/10.3390/cancers13061321 |
Appears in Collections: | Articles publicats en revistes (Odontoestomatologia) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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