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http://hdl.handle.net/2445/184412
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DC Field | Value | Language |
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dc.contributor.author | Zaragoza-Puchol, Daniel | - |
dc.contributor.author | Ortiz, Javier E. | - |
dc.contributor.author | Orden, Alejandro A. | - |
dc.contributor.author | Sánchez, Marianela | - |
dc.contributor.author | Palermo, Jorge | - |
dc.contributor.author | Tapia, Alejandro | - |
dc.contributor.author | Bastida Armengol, Jaume | - |
dc.contributor.author | Feresin, Gabriela E. | - |
dc.date.accessioned | 2022-03-25T09:40:16Z | - |
dc.date.available | 2022-03-25T09:40:16Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | http://hdl.handle.net/2445/184412 | - |
dc.description.abstract | Plants in the Amaryllidaceae family synthesize a diversity of bioactive alkaloids. Some of these plant species are not abundant and have a low natural multiplication rate. The aims of this work were the alkaloids analysis of a Habranthus cardenasianus bulbs extract, the evaluation of its inhibitory activity against cholinesterases, and to test several propagation strategies for biomass production. Eleven compounds were characterized by GC-MS in the alkaloid extract, which showed a relatively high proportion of tazettine. The known alkaloids tazettine, haemanthamine, and the epimer mixture haemanthidine/6-epi-haemanthidine were isolated and identified by spectroscopic methods. Inhibitory cholinesterases activity was not detected. Three forms of propagation were performed: bulb propagation from seed, cut-induced bulb division, and micropropagated bulbs. Finally, different imbibition and post-collection times were evaluated in seed germination assays. The best propagation method was cut-induced bulb division with longitudinal cuts into quarters (T1) while the best conditions for seed germination were 0-day of post-collection and two days of imbibition. The alkaloids analyses of the H. cardenasianus bulbs showed that they are a source of anti-tumoral alkaloids, especially pretazettine (tazettine) and T1 is a sustainable strategy for its propagation and domestication to produce bioactive alkaloids. Keywords: Amaryllidaceae; bioactive alkaloids; GC-MS; propagation methods; biomass production | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/molecules26010192 | - |
dc.relation.ispartof | Molecules, 2021, vol. 26, num. 1, p. 192 | - |
dc.relation.uri | https://doi.org/10.3390/molecules26010192 | - |
dc.rights | cc-by (c) Zaragoza-Puchol, Daniel et al., 2021 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) | - |
dc.subject.classification | Amaril·lidàcies | - |
dc.subject.classification | Alcaloides | - |
dc.subject.classification | Compostos bioactius | - |
dc.subject.other | Amaryllidaceae | - |
dc.subject.other | Alkaloids | - |
dc.subject.other | Bioactive compounds | - |
dc.title | Alkaloids Analysis of Habranthus cardenasianus (Amaryllidaceae), Anti-Cholinesterase Activity and Biomass Production by Propagation Strategies | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 720662 | - |
dc.date.updated | 2022-03-25T09:40:16Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) |
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File | Description | Size | Format | |
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720662.pdf | 1.62 MB | Adobe PDF | View/Open |
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