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Title: | Alkaloids Analysis of Habranthus cardenasianus (Amaryllidaceae), Anti-Cholinesterase Activity and Biomass Production by Propagation Strategies |
Author: | Zaragoza-Puchol, Daniel Ortiz, Javier E. Orden, Alejandro A. Sánchez, Marianela Palermo, Jorge Tapia, Alejandro Bastida Armengol, Jaume Feresin, Gabriela E. |
Keywords: | Amaril·lidàcies Alcaloides Compostos bioactius Amaryllidaceae Alkaloids Bioactive compounds |
Issue Date: | 2021 |
Publisher: | MDPI |
Abstract: | Plants in the Amaryllidaceae family synthesize a diversity of bioactive alkaloids. Some of these plant species are not abundant and have a low natural multiplication rate. The aims of this work were the alkaloids analysis of a Habranthus cardenasianus bulbs extract, the evaluation of its inhibitory activity against cholinesterases, and to test several propagation strategies for biomass production. Eleven compounds were characterized by GC-MS in the alkaloid extract, which showed a relatively high proportion of tazettine. The known alkaloids tazettine, haemanthamine, and the epimer mixture haemanthidine/6-epi-haemanthidine were isolated and identified by spectroscopic methods. Inhibitory cholinesterases activity was not detected. Three forms of propagation were performed: bulb propagation from seed, cut-induced bulb division, and micropropagated bulbs. Finally, different imbibition and post-collection times were evaluated in seed germination assays. The best propagation method was cut-induced bulb division with longitudinal cuts into quarters (T1) while the best conditions for seed germination were 0-day of post-collection and two days of imbibition. The alkaloids analyses of the H. cardenasianus bulbs showed that they are a source of anti-tumoral alkaloids, especially pretazettine (tazettine) and T1 is a sustainable strategy for its propagation and domestication to produce bioactive alkaloids. Keywords: Amaryllidaceae; bioactive alkaloids; GC-MS; propagation methods; biomass production |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/molecules26010192 |
It is part of: | Molecules, 2021, vol. 26, num. 1, p. 192 |
URI: | http://hdl.handle.net/2445/184412 |
Related resource: | https://doi.org/10.3390/molecules26010192 |
ISSN: | 1420-3049 |
Appears in Collections: | Articles publicats en revistes (Biologia, Sanitat i Medi Ambient) |
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