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Title: Animal protein intake is inversely associated with mortality in older adults: the InCHIANTI study
Author: Meroño, Tomás
Zamora-Ros, Raul
Hidalgo Liberona, Nicole
Rabassa Bonet, Montserrat
Bandinelli, Stefania
Ferrucci, Luigi
Fedecostante, Massimiliano
Cherubini, Antonio
Andrés Lacueva, Ma. Cristina
Keywords: Mortalitat
Persones grans
Older people
Issue Date: 27-Nov-2021
Publisher: Gerontological Society of America
Abstract: Abstract Background In general, plant protein intake was inversely associated with mortality in studies in middle-aged adults. Our aim was to evaluate the long-term associations of animal and plant protein intake with mortality in older adults. Methods A prospective cohort study including 1 139 community-dwelling older adults (mean age 75 years, 56% women) living in Tuscany, Italy, followed for 20 years (InCHIANTI study) was analyzed. Dietary intake by food frequency questionnaires and clinical information were assessed 5 times during the follow-up. Protein intakes were expressed as percentages of total energy. Time-dependent Cox regression models adjusted for confounders were used to assess the association between plant and animal protein intake, and mortality. Results During the 20 years of follow-up (mean: 12 years), 811 deaths occurred (292 of cardiovascular- and 151 of cancer-related causes). Animal protein intake was inversely associated with all-cause (hazard ratio [HR] per 1% of total energy from protein increase, 95% confidence interval [CI]: 0.96, 0.93-0.99) and cardiovascular mortality (HR per 1% of total energy from protein increase, 95% CI: 0.93, 0.87-0.98). Plant protein intake showed no association with any of the mortality outcomes, but an interaction with baseline hypertension was found for all-cause and cardiovascular mortality (p < .05). Conclusions Animal protein was inversely associated with all-cause and cardiovascular mortality in older adults. Further studies are needed to provide recommendations on dietary protein intake for older adults.
Note: Versió postprint del document publicat a:
It is part of: Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences, 2021
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ISSN: 1079-5006
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)

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