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Title: A forensic population database in El Salvador: 58 STRs and 94 SNPs
Author: Casals López, Ferran
Rasal, Raquel
Anglada, Roger
Tormo, Marc
Bonet, Núria
Rivas, Nury
Vásquez, Patricia
Calafell, Francesc
Keywords: Persones desaparegudes
El Salvador
Genètica humana
Disappeared persons
El Salvador
Human genetics
Issue Date: 1-Mar-2022
Publisher: Elsevier B.V.
Abstract: We have genotyped the 58 STRs (27 autosomal, 24 Y-STRs and 7 X-STRs) and 94 autosomal SNPs in Illumina ForenSeq Primer Mix A in a sample of 248 men and 143 women from El Salvador, Central America. Regional division (Centro, Oriente, Occidente) showed in almost all cases FST values not significantly different from 0, and further analyses were applied only to the undivided, country-wide population. The overall random match probability (RMP) decreased from 6.79 × 10−31 in length-based genotypes in the 27 autosomal STRs to 1.47 × 10−34 in repeat-sequence based genotypes. Combining the autosomal loci in this set, RMP reaches 2.97 × 10−70. In a population genetic analysis, El Salvador showed the lowest FST values with US Hispanics both for autosomal and X-STRs; however, it was much closer to Native Americans for the latter than for the former, in accordance with the well-known gender-biased admixture that created most Latin American populations.
Note: Versió postprint del document publicat a:
It is part of: Forensic Science International-Genetics, 2022, vol. 57
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ISSN: 1872-4973
Appears in Collections:Articles publicats en revistes (Genètica, Microbiologia i Estadística)

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