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Title: Effect of Hepatitis E virus RNA universal blood donor screening, Catalonia, Spain, 2017-2020
Author: Bes, Marta
Costafreda Salvany, M. Isabel (Maria Isabel)
Riveiro-Barciela, Mar
Piron, Maria
Rico, Angie
Quer, Josep
Puig, Lluís
Sauleda, Silvia
Keywords: Virus de l'hepatitis E
Hepatitis vírica
Carn de porc
Transfusió de sang
Hepatitis E virus
Viral hepatitis
Blood transfusion
Issue Date: 1-Jan-2022
Publisher: Centers for Disease Control and Prevention
Abstract: Hepatitis E virus (HEV) is the major cause of acute viral hepatitis in several countries in Europe. HEV is acquired mainly by consumption of contaminated pork but can also be transmitted through blood transfusion. HEV infection is usually self-limited but can become persistent in immunocompromised persons. During the first 30 months of HEV RNA universal screening of blood donations in Catalonia, Spain, we identifi ed 151 HEV RNA-positive donations (1/4,341 blood donations). Most infected donors reported consumption of pates and sausages, and 58% were negative for HEV IgM and IgG. All HEV isolates belonged to geno-type 3. All infected donors spontaneously resolved the infection, and no neurologic symptoms and reinfections were observed after 1 year of follow-up. Since the implementation of HEV RNA universal screening, no new cases of transfusion-transmitted HEV infection were reported. Our data indicate HEV screening of blood donations provides safer blood for all recipients, especially for immunosuppressed persons
Note: Reproducció del document publicat a:
It is part of: Emerging Infectious Diseases, 2022, vol. 28, num. 1, p. 157-165
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ISSN: 1080-6040
Appears in Collections:Articles publicats en revistes (Genètica, Microbiologia i Estadística)

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