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http://hdl.handle.net/2445/195064
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DC Field | Value | Language |
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dc.contributor.author | Hernández-Meneses, Marta | - |
dc.contributor.author | Llopis Pérez, Jaime | - |
dc.contributor.author | Sandoval, Elena | - |
dc.contributor.author | Ninot, Salvador | - |
dc.contributor.author | Almela, M. (Manel) | - |
dc.contributor.author | Falces Salvador, Carles | - |
dc.contributor.author | Pericàs, Juan M. | - |
dc.contributor.author | Vidal, Barbara | - |
dc.contributor.author | Perissinotti, Andrés | - |
dc.contributor.author | Marco Reverté, Francesc | - |
dc.contributor.author | Mestres, Carlos A. | - |
dc.contributor.author | Pare i Bardera, J. Carles | - |
dc.contributor.author | García de la María, Cristina | - |
dc.contributor.author | Cuervo Requena, Guillermo | - |
dc.contributor.author | Quintana, Eduard | - |
dc.contributor.author | Tolosana, José M. (José María) | - |
dc.contributor.author | Moreno Camacho, Ma. Asunción | - |
dc.contributor.author | Miró Meda, José M. | - |
dc.contributor.author | Hospital Clinic Infective Endocarditis Team Investigators | - |
dc.date.accessioned | 2023-03-10T17:31:31Z | - |
dc.date.available | 2023-03-10T17:31:31Z | - |
dc.date.issued | 2022-10-14 | - |
dc.identifier.issn | 2328-8957 | - |
dc.identifier.uri | http://hdl.handle.net/2445/195064 | - |
dc.description.abstract | Background: Studies investigating cardiac implantable electronic device infective endocarditis (CIED-IE) epidemiological changes and prognosis over long periods of time are lacking. Methods: Retrospective single cardiovascular surgery center cohort study of definite CIED-IE episodes between 1981-2020. A comparative analysis of two periods (1981-2000 vs 2001-2020) was conducted to analyze changes in epidemiology and outcome over time. Results: One-hundred and thirty-eight CIED-IE episodes were diagnosed: 25 (18%) first period and 113 (82%) second. CIED-IE was 4.5 times more frequent in the second period, especially in implantable cardiac defibrillators. Age (63 [53-70] vs 71 [63-76] years, P < .01), comorbidities (CCI 3.0 [2-4] vs 4.5 [3-6], P > .01), nosocomial infections (4% vs 15.9%, P = .02) and transfers from other centers (8% vs 41.6%, P < .01) were significantly more frequent in the second period, as were methicillin-resistant coagulase-negative staphylococcal (MR-CoNS) (0% vs 13.3%, P < .01) and Enterococcus spp. (0% vs 5.3%, P = .01) infections, pulmonary embolism (0% vs 10.6%, P < .01) and heart failure (12% vs 28.3%, p < .01). Second period surgery rates were lower (96% vs 87.6%, P = .09), and there were no differences in in-hospital (20% vs 11.5%, P = .11) and one-year mortalities (24% vs 15%, P = .33), or relapses (8% vs 5.3%, P = 0.65). Multivariate analysis showed Charlson index (hazard ratios [95% confidence intervals]; 1.5 [1.16-1.94]) and septic shock (23.09 [4.57-116.67]) were associated with a worse prognosis, whereas device removal (0.11 [.02-.57]), transfers (0.13 [.02-0.95]), and second-period diagnosis (0.13 [.02-.71]) were associated with better one-year outcomes. Conclusions: CIED-IE episodes increased more than four-fold during last 40 years. Despite CIED-IE involved an older population with more comorbidities, antibiotic-resistant MR-CoNS, and complex devices, one-year survival improved. | - |
dc.format.extent | 11 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Oxford University Press | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1093/ofid/ofac547 | - |
dc.relation.ispartof | Open Forum Infectious Diseases, 2022, vol. 9, num. 11, p. 1-11 | - |
dc.relation.uri | https://doi.org/10.1093/ofid/ofac547 | - |
dc.rights | cc-by-nc-nd (c) Hernández-Meneses, Marta et al., 2022 | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.source | Articles publicats en revistes (Genètica, Microbiologia i Estadística) | - |
dc.subject.classification | Pronòstic mèdic | - |
dc.subject.classification | Epidemiologia | - |
dc.subject.classification | Endocarditis | - |
dc.subject.other | Prognosis | - |
dc.subject.other | Epidemiology | - |
dc.subject.other | Endocarditis | - |
dc.title | Forty-Year Trends in Cardiac Implantable Electronic Device Infective Endocarditis | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 729627 | - |
dc.date.updated | 2023-03-10T17:31:31Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.idimarina | 9332596 | - |
dc.identifier.pmid | 36381626 | - |
Appears in Collections: | Articles publicats en revistes (Genètica, Microbiologia i Estadística) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) |
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