Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/198593
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jordán, Maria | - |
dc.contributor.author | Wojtys-Tekiel, Sylwia | - |
dc.contributor.author | Merino Montero, Susana | - |
dc.contributor.author | Tomàs Magaña, Juan | - |
dc.contributor.author | Kaszowska, Marta | - |
dc.date.accessioned | 2023-05-30T12:36:24Z | - |
dc.date.available | 2023-05-30T12:36:24Z | - |
dc.date.issued | 2023-03-01 | - |
dc.identifier.issn | 1661-6596 | - |
dc.identifier.uri | http://hdl.handle.net/2445/198593 | - |
dc.description.abstract | The Edwardsiella genus presents five different pathogenic species: Edwardsiella tarda, E. anguillarum, E. piscicida, E. hoshinae and E. ictaluri. These species cause infections mainly in fish, but they can also infect reptiles, birds or humans. Lipopolysaccharide (endotoxin) plays an important role in the pathogenesis of these bacteria. For the first time, the chemical structure and genomics of the lipopolysaccharide (LPS) core oligosaccharides of E. piscicida, E. anguillarum, E. hoshinae and E. ictaluri were studied. The complete gene assignments for all core biosynthesis gene functions were acquired. The structure of core oligosaccharides was investigated by 1H and 13C nuclear magnetic resonance (NMR) spectroscopy. The structures of E. piscicida and E. anguillarum core oligosaccharides show the presence of !3,4)-L-glycero- -D-manno-Hepp, two terminal -D-Glcp, !2,3,7)-L-glycero- -Dmanno- Hepp,!7)-L-glycero- -D-manno-Hepp, terminal -D-GlcpN, two!4)- -D-GalpA,! 3)- -DGlcpNAc, terminal -D-Galp and !5-substituted Kdo. E. hoshinare core oligosaccharide shows only one terminal -D-Glcp, and instead of terminal -D-Galp a terminal -D-GlcpNAc. E. ictaluri core oligosaccharide shows only one terminal -D-Glcp, one !4)- -D-GalpA and do not have terminal -D-GlcpN (see complementary figure). | - |
dc.format.extent | 17 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/ijms24054768 | - |
dc.relation.ispartof | International Journal of Molecular Sciences, 2023, vol. 24, num. 5, p. 4768 | - |
dc.relation.uri | https://doi.org/10.3390/ijms24054768 | - |
dc.rights | cc-by (c) Jordán, Maria et al., 2023 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Genètica, Microbiologia i Estadística) | - |
dc.subject.classification | Bacteris gramnegatius | - |
dc.subject.classification | Genòmica | - |
dc.subject.classification | Oligosacàrids | - |
dc.subject.classification | Espectroscòpia de ressonància magnètica nuclear | - |
dc.subject.other | Gram-negative bacteria | - |
dc.subject.other | Genomics | - |
dc.subject.other | Oligosaccharides | - |
dc.subject.other | Nuclear magnetic resonance spectroscopy | - |
dc.title | Structural diversity among Edwarsiellaceae core oligosaccharides. | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 733595 | - |
dc.date.updated | 2023-05-30T12:36:24Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Genètica, Microbiologia i Estadística) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
733595.pdf | 6.74 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License