Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/206230
Title: | Ablation Lesion Assessment with MRI |
Author: | Mont Girbau, Lluís Roca Luque, Ivo Althoff, Till F. |
Keywords: | Malalties cardiovasculars Ressonància magnètica Cardiovascular diseases Magnetic resonance |
Issue Date: | 11-Dec-2021 |
Publisher: | Radcliff Cardiology |
Abstract: | Late gadolinium enhancement (LGE) MRI is capable of detecting not only native cardiac fibrosis, but also ablation-induced scarring. Thus, it offers the unique opportunity to assess ablation lesions non-invasively. In the atrium, LGE-MRI has been shown to accurately detect and localise gaps in ablation lines. With a negative predictive value close to 100% it can reliably rule out pulmonary vein reconnection non-invasively and thus may avoid unnecessary invasive repeat procedures where a pulmonary vein isolation only approach is pursued. Even LGE-MRI-guided repeat pulmonary vein isolation has been demonstrated to be feasible as a standalone approach. LGE-MRI-based lesion assessment may also be of value to evaluate the efficacy of ventricular ablation. In this respect, the elimination of LGE-MRI-detected arrhythmogenic substrate may serve as a potential endpoint, but validation in clinical studies is lacking. Despite holding great promise, the widespread use of LGE-MRI is still limited by the absence of standardised protocols for image acquisition and post-processing. In particular, reproducibility across different centres is impeded by inconsistent thresholds and internal references to define fibrosis. Thus, uniform methodological and analytical standards are warranted to foster a broader implementation in clinical practice. |
Note: | Reproducció del document publicat a: https://doi.org/10.15420/aer.2021.63 |
It is part of: | Arrhythm Electrophysiol Rev, 2022, vol. 11, num. 1 |
URI: | http://hdl.handle.net/2445/206230 |
Related resource: | https://doi.org/10.15420/aer.2021.63 |
ISSN: | 2050-3377 |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Ablation Lesion Assessment with MRI_ArrythmiaAndElectrophisiology.pdf | 2.86 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License