Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/208066
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Pinto, Diana | - |
dc.contributor.author | Ferreira, Ana Sofia | - |
dc.contributor.author | Lozano-Castellón, Julián | - |
dc.contributor.author | Laveriano-Santos, Emily P. | - |
dc.contributor.author | Lamuela Raventós, Rosa Ma. | - |
dc.contributor.author | Vallverdú i Queralt, Anna | - |
dc.contributor.author | Delerue-Matos, Cristina | - |
dc.contributor.author | Rodrigues, Francesca | - |
dc.date.accessioned | 2024-02-27T13:19:34Z | - |
dc.date.available | 2024-02-27T13:19:34Z | - |
dc.date.issued | 2023-08-28 | - |
dc.identifier.issn | 2297-8739 | - |
dc.identifier.uri | http://hdl.handle.net/2445/208066 | - |
dc.description.abstract | <p><span style="color:rgb( 46 , 46 , 46 )">Chestnut shells (CS), the principal by-product of the chestnut processing industry, contain high concentrations of flavonoids and other polyphenols with huge interest for the nutraceuticals field. Nonetheless, the bioaccessibility and bioactivity of phytochemicals can be influenced by their digestibility, making it imperative to evaluate these activities prior to application of CS as a nutraceutical ingredient. This work aims to appraise the effects of in vitro simulated gastrointestinal digestion on the bioaccessibility, bioactivity, and metabolic profiling of CS. An increase in the total phenolic and flavonoid contents, antioxidant/antiradical properties, radical scavenging capacity, and inhibition on acetylcholinesterase activity was evidenced during in vitro simulated digestion. Metabolomic profiling by LC-ESI-LTQ-Orbitrap-MS revealed changes during the simulated digestion, particularly in phenolic compounds (46% of total compounds annotated), lipids (22%), phenylpropanoids (9%), organic acids (7%), carbohydrates (5%), nucleosides (5%), amino acids (4%), and alcohols (1%). Phenolic acids (gallic acid, syringic acid, and hydroxyphenylacetic acid) and flavonoids (epicatechin) were the major polyphenolic classes identified. The heatmap-positive correlations highlighted that the bioactivity of CS is closely related to the phenolic compounds and their bioaccessibility. These findings suggest the reuse of CS as a potential nutraceutical ingredient with antioxidant and neuroprotective effects, encouraging the use of appropriate extraction and/or encapsulation techniques to enhance the bioaccessibility of phenolic compounds. © 2023 by the authors.</span></p> | - |
dc.format.extent | 1 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/separations10090471 | - |
dc.relation.ispartof | Separations, 2023, vol. 10, num.9 | - |
dc.relation.uri | https://doi.org/10.3390/separations10090471 | - |
dc.rights | cc-by (c) Pinto, D. et al., 2023 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) | - |
dc.subject.classification | Metabolòmica | - |
dc.subject.classification | Polifenols | - |
dc.subject.other | Metabolomics | - |
dc.subject.other | Polyphenols | - |
dc.title | Exploring the Impact of In Vitro Gastrointestinal Digestion in the Bioaccessibility of Phenolic-Rich Chestnut Shells: A Preliminary Study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 741409 | - |
dc.date.updated | 2024-02-27T13:19:34Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
838886.pdf | 1.58 MB | Adobe PDF | View/Open |
This item is licensed under a
Creative Commons License