Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/208424
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Abrisqueta, Pau | - |
dc.contributor.author | Nadeu, Ferran | - |
dc.contributor.author | Bosch Schips, Jan | - |
dc.contributor.author | Iacoboni, Gloria | - |
dc.contributor.author | Serna, Angel | - |
dc.contributor.author | Cabirta, Alba | - |
dc.contributor.author | Yáñez, Lucrecia | - |
dc.contributor.author | Quintanilla Martinez, Leticia | - |
dc.contributor.author | Bosch, Francesc | - |
dc.date.accessioned | 2024-03-05T12:52:09Z | - |
dc.date.available | 2024-03-05T12:52:09Z | - |
dc.date.issued | 2023-11-01 | - |
dc.identifier.issn | 0305-7372 | - |
dc.identifier.uri | http://hdl.handle.net/2445/208424 | - |
dc.description.abstract | Richter transformation (RT) refers to the progression of chronic lymphocytic leukemia, the most prevalent leukemia among adults, into a highly aggressive lymphoproliferative disorder, primarily a diffuse large B-cell lymphoma. This is a severe complication that continues to be a therapeutic challenge and remains an unmet medical need. Over the last five years, significant advances have occurred in uncovering the biological processes leading to the RT, refining criteria for properly diagnose RT from other entities, and exploring new therapeutic options beyond the ineffective chemotherapy. This review summarizes current knowledge in RT, including recent advances in the understanding of the pathogenesis of RT, in the classification of RT, and in the development of novel therapeutic strategies for this grave complication. | - |
dc.format.extent | 18 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier BV | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1016/j.ctrv.2023.102619 | - |
dc.relation.ispartof | Cancer Treatment Reviews, 2023, vol. 120, p. 102619 | - |
dc.relation.uri | https://doi.org/10.1016/j.ctrv.2023.102619 | - |
dc.rights | cc by-nc-nd (c) Abrisqueta, Pau et al., 2023 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Leucèmia limfocítica crònica | - |
dc.subject.classification | Mutació (Biologia) | - |
dc.subject.other | Chronic lymphocytic leukemia | - |
dc.subject.other | Mutation (Biology) | - |
dc.title | From genetics to therapy: Unraveling the complexities of Richter transformation in chronic lymphocytic leukemia | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2023-11-24T09:29:04Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 37660626 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
PIIS0305737223001123.pdf | 12.48 MB | Adobe PDF | View/Open |
This item is licensed under a
Creative Commons License