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http://hdl.handle.net/2445/212660
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DC Field | Value | Language |
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dc.contributor.author | Picó Pérez, Maria | - |
dc.contributor.author | Fullana, Miquel A. | - |
dc.contributor.author | Albajes Eizagirre, Anton | - |
dc.contributor.author | Vega, Daniel | - |
dc.contributor.author | Marco Pallarés, Josep | - |
dc.contributor.author | Vilar, Ana | - |
dc.contributor.author | Chamorro, Jacobo | - |
dc.contributor.author | Felmingham, Kim L. | - |
dc.contributor.author | Harrison, Ben J. | - |
dc.contributor.author | Radua, Joaquim | - |
dc.contributor.author | Soriano Mas, Carles | - |
dc.date.accessioned | 2024-06-07T16:42:07Z | - |
dc.date.available | 2024-06-07T16:42:07Z | - |
dc.date.issued | 2022-01-11 | - |
dc.identifier.issn | 0033-2917 | - |
dc.identifier.uri | http://hdl.handle.net/2445/212660 | - |
dc.description.abstract | Background: Cognitive-behavior therapy (CBT) is a well-established first-line intervention for anxiety-related disorders, including specific phobia, social anxiety disorder, panic disorder/agoraphobia, generalized anxiety disorder, obsessive-compulsive disorder, and posttraumatic stress disorder. Several neural predictors of CBT outcome for anxiety-related disorders have been proposed, but previous results are inconsistent. Methods: We conducted a systematic review and meta-analysis of task-based functional magnetic resonance imaging (fMRI) studies investigating whole-brain predictors of CBT outcome in anxiety-related disorders (17 studies, n=442). Results: Across different tasks, we observed that brain response in a network of regions involved in salience and interoception processing, encompassing frontoinsular (the right inferior frontal gyrus-anterior insular cortex) and fronto-limbic (the dorsomedial prefrontal cortex-dorsal anterior cingulate cortex) cortices was strongly associated with a positive CBT outcome. Conclusions: Our results suggest that there are robust neural predictors of CBT outcome in anxiety-related disorders that may eventually lead (probably in combination with other data) to develop personalized approaches for the treatment of these mental disorders. | - |
dc.format.extent | 9 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Cambridge University Press (CUP) | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1017/S0033291721005444 | - |
dc.relation.ispartof | Psychological Medicine, 2023, vol. 53, num.8, p. 3387-3395 | - |
dc.relation.uri | https://doi.org/10.1017/S0033291721005444 | - |
dc.rights | (c) Cambridge University Press (CUP), 2023 | - |
dc.source | Articles publicats en revistes (Psicologia Social i Psicologia Quantitativa) | - |
dc.subject.classification | Ansietat | - |
dc.subject.classification | Escorça cerebral | - |
dc.subject.classification | Trastorns de la cognició | - |
dc.subject.classification | Imatges per ressonància magnètica | - |
dc.subject.other | Anxiety | - |
dc.subject.other | Cerebral cortex | - |
dc.subject.other | Cognition disorders | - |
dc.subject.other | Magnetic resonance imaging | - |
dc.title | Neural predictors of cognitive-behavior therapy outcome in anxiety-related disorders: A meta-analysis of task-based fMRI studies | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 718586 | - |
dc.date.updated | 2024-06-07T16:42:12Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació) Articles publicats en revistes (Psicologia Social i Psicologia Quantitativa) Articles publicats en revistes (Medicina) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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File | Description | Size | Format | |
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245789.pdf | 282.33 kB | Adobe PDF | View/Open |
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