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Title: | Is long-term follow-up solely by imaging tests safe in non-operated pancreatic neuroendocrine tumors? |
Author: | Polette, Daniela Busquets Barenys, Juli Secanella Medayo, Lluis Sorribas Grifell, María Peláez Serra, Nuria Uribe, Catalina Martinez-Carnicero, Laura Salord, Silvia Guerrero Pérez, Fernando Vercher Conejero, José Luís Teulé Vega, Àlex Fabregat Prous, Joan |
Keywords: | Càncer de pàncrees Diagnòstic per la imatge Endoscòpia Pancreas cancer Diagnostic imaging Endoscopy |
Issue Date: | Apr-2024 |
Publisher: | ARÁN EDICIONES, S.L. |
Abstract: | Introduction: the diagnosis of asymptomatic sporadic nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs) has increased significantly due to the widespread use of high-resolution imaging tests, which is why the most appropriate management at the time of diagnosis is the subject of debate, as is how to follow-up patients. Aims: the objective of this study was to analyze the frequency of imaging and endoscopic studies performed during long-term follow-up. Methods: a retrospective review was performed of a database collected between January 2008 and December 2020 of patients with an incidental diagnosis of small NF-PNETs; follow-up was closed in March 2023. The imaging tests performed at the time of diagnosis and long-term follow-up were recorded. Growing less than 1 mm per year has not been considered as a worrisome feature. Follow-up was performed through imaging tests, considering endoscopic cytology for lesions with a faster grow rate. Results: fifty-eight patients were included; the median age was 69 years. The initial mean size of the lesions studied was 12.79 mm (5-27). Follow-up was carried out only with computed tomography (CT) or magnetic resonance imaging (MRI). The initial size did not influence the behavior of the lesion in a statistically significant manner. Twenty-eight tumors (45 %) increased in size, with a growth equal to or less than 4 mm in 24 cases. The mean follow-up time was 82.41 months (12-164). No patient developed metastasis or died from PNET progression. Conclusions: the follow-up of neuroendocrine tumors of small size can be performed safely with only imaging tests. |
Note: | Reproducció del document publicat a: https://doi.org/10.17235/reed.2023.9293/2022 |
It is part of: | Revista Española de Enfermedades Digestivas, 2024, vol. 116, num.4, p. 209-215 |
URI: | http://hdl.handle.net/2445/214862 |
Related resource: | https://doi.org/10.17235/reed.2023.9293/2022 |
ISSN: | 1130-0108 |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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860375.pdf | 920.19 kB | Adobe PDF | View/Open |
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