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https://hdl.handle.net/2445/216332
Title: | Quantitative Ultrasound Image Analysis of Axillary Lymph Nodes to Diagnose Metastatic Involvement in Breast Cancer |
Author: | Coronado Gutiérrez, David Santamaría, Gorane Ganau, Sergi Bargalló, Xavier Orlando, Stefania Oliva Brañas, M. Eulalia Pérez Moreno, Álvaro Burgos Artizzu, Xavier P. |
Keywords: | Ecografia Metàstasi Diagnòstic per la imatge Càncer de mama Nodes limfàtics Aprenentatge automàtic Ultrasonic imaging Metastasis Diagnostic imaging Breast cancer Lymph nodes Machine learning |
Issue Date: | Nov-2019 |
Publisher: | Elsevier |
Abstract: | This study aimed to assess the potential of state-of-the-art ultrasound analysis techniques to non-invasively diagnose axillary lymph nodes involvement in breast cancer. After exclusion criteria, 105 patients were selected from two different hospitals. The 118 lymph node ultrasound images taken from these patients were divided into 53 cases and 65 controls, which made up the study series. The clinical outcome of each node was verified by ultrasound-guided fine needle aspiration, core needle biopsy or surgical biopsy. The achieved accuracy of the proposed method was 86.4%, with 84.9% sensitivity and 87.7% specificity. When tested on breast cancer patients only, the proposed method improved the accuracy of the sonographic assessment of axillary lymph nodes performed by expert radiologists by 9% (87.0% vs 77.9%). In conclusion, the results demonstrate the potential of ultrasound image analysis to detect the microstructural and compositional changes that occur in lymph nodes because of metastatic involvement. |
Note: | Reproducció del document publicat a: https://doi.org/10.1016/j.ultrasmedbio.2019.07.413 |
It is part of: | Ultrasound in Medicine and Biology, 2019, vol. 45, num.11, p. 2932-2945 |
URI: | https://hdl.handle.net/2445/216332 |
Related resource: | https://doi.org/10.1016/j.ultrasmedbio.2019.07.413 |
ISSN: | 0301-5629 |
Appears in Collections: | Articles publicats en revistes (Fonaments Clínics) |
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