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Title: FiltekTM Silorane and FiltekTM Supreme XT resins: tissue reaction after subcutaneous implantation in isogenic mice
Author: Ruiz de Castañeda, Esther
Silva, Léa Assed Bezerra da
Gatón Hernández, Patrícia
Consolaro, Alberto
González Rodríguez, Encarnación
Silva, Raquel Assed Bezerra da
Queiroz, Alexandra Mussolino de
Nelson Filho, Paulo
Keywords: Materials dentals
Gomes i resines
Dental materials
Gums and resins
Issue Date: 2011
Publisher: Fundação Odontológica de Ribeirão Preto
Abstract: The aim of this study was to evaluate the tissue compatibility of a silorane-based resin system (FiltekTM Silorane) and a methacrylatebased nanoparticle resin (FiltekTM Supreme XT) after implantation in the subcutaneous connective tissue of isogenic mice. One hundred and thirty five male isogenic BALB/c mice were randomly assigned to 12 experimental and 3 control groups, according to the implanted material and the experimental period of 7, 21 and 63 days. At the end of each period, the animals were killed and the tubes with the surrounding tissues were removed and processed for microscopic analysis. Samples were subjected to a descriptive and a semi-quantitative analyses using a 4-point scoring system (0-3) to evaluate the collagen fiber formation and inflammatory infiltrate. Data were statistically analyzed using the Kruskal Wallis test (a=0.05). The results showed that there was no significant difference between the experimental and control groups considering the three evaluation periods (p>0.05). The silorane-based and the methacrylate-based nanoparticle resins presented similar tissue response to that of the empty tube (control group) after subcutaneous implantation in isogenic mice.
Note: Reproducció del document publicat a:
It is part of: Brazilian Dental Journal, 2011, vol. 22, núm. 2, p. 105-110
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ISSN: 0103-6440
Appears in Collections:Articles publicats en revistes (Odontoestomatologia)

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