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https://hdl.handle.net/2445/220012| Title: | Generation of the CTRL EiPS J9 mR6F-8 iPSC line derived from healthy human outgrowth blood endothelial cells (BOECs) using mRNA reprogramming methodology |
| Author: | Selvitella, Silvia Franco, Marta Pérez Aran, Begoña Veiga, Anna Kuebler, Bernd |
| Keywords: | Enginyeria genètica Endoteli Cèl·lules Genetic engineering Endothelium Cells |
| Issue Date: | 1-Dec-2024 |
| Publisher: | Elsevier BV |
| Abstract: | mRNA reprogramming is a technology for generating iPSCs with high efficiency and safety. However, it is not suitable for reprogramming non-adherent cells, the primary cell type in blood. An alternative is to obtain adherent cells from blood for this technology. To validate this approach, we generated a human iPSC line from blood outgrowth endothelial cells (BOECs) using mRNA-based reprogramming. The resulting line, CTRL EiPS J9 mR6F-8, meets iPSC criteria, including an undifferentiated state, pluripotency, genome integrity. This line is available upon request. |
| Note: | Reproducció del document publicat a: https://doi.org/10.1016/j.scr.2024.103606 |
| It is part of: | Stem Cell Research, 2024, vol. 81 |
| URI: | https://hdl.handle.net/2445/220012 |
| Related resource: | https://doi.org/10.1016/j.scr.2024.103606 |
| ISSN: | 1876-7753 |
| Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 1-s2.0-S1873506124003040-main.pdf | 5.48 MB | Adobe PDF | View/Open |
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